General Information
| Gene ID | 4194 |
|---|---|
| Gene Symbol | MDM4 |
| Gene Name | Mdm4 p53 binding protein homolog (mouse) |
| Gene Type | protein-coding |
| Cytoband | 1q32 |
| Ensembl ID | ENSG00000198625 |
| #miR regulators | 26 |
| Omim ID | 602704 |
| Gene ontology |
GO:0000122: negative regulation of transcription from RNA polymerase II promoter GO:0006461: protein complex assembly GO:0043066: negative regulation of apoptotic process GO:0008283: cell proliferation GO:0008284: positive regulation of cell proliferation GO:0008285: negative regulation of cell proliferation GO:0050821: protein stabilization GO:0030330: DNA damage response, signal transduction by p53 class mediator GO:0042177: negative regulation of protein catabolic process GO:0045023: G0 to G1 transition GO:0071157: negative regulation of cell cycle arrest GO:0071456: cellular response to hypoxia GO:0005634: nucleus GO:0005515: protein binding GO:0008270: zinc ion binding GO:0019899: enzyme binding |
| KEGG pathways |
4115: p53 signaling pathway |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 21159888 | Comprehensive mapping of p53 pathway alterations reveals an apparent role for both SNP309 and MDM2 amplification in sarcomagenesis. | yes | no |
| title | all | all |