Results for MDM4

General Information

Gene ID 4194
Gene Symbol MDM4
Gene Name Mdm4 p53 binding protein homolog (mouse)
Gene Type protein-coding
Cytoband 1q32
Ensembl ID ENSG00000198625
#miR regulators 26
Omim ID 602704
Gene ontology GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0006461: protein complex assembly
GO:0043066: negative regulation of apoptotic process
GO:0008283: cell proliferation
GO:0008284: positive regulation of cell proliferation
GO:0008285: negative regulation of cell proliferation
GO:0050821: protein stabilization
GO:0030330: DNA damage response, signal transduction by p53 class mediator
GO:0042177: negative regulation of protein catabolic process
GO:0045023: G0 to G1 transition
GO:0071157: negative regulation of cell cycle arrest
GO:0071456: cellular response to hypoxia
GO:0005634: nucleus
GO:0005515: protein binding
GO:0008270: zinc ion binding
GO:0019899: enzyme binding
KEGG pathways 4115: p53 signaling pathway

PubMed abstracts associated with MDM4

PMID Title Tumor Value
21159888 Comprehensive mapping of p53 pathway alterations reveals an apparent role for both SNP309 and MDM2 amplification in sarcomagenesis. yes no
title all all