General Information
Gene ID | 4221 |
---|---|
Gene Symbol | MEN1 |
Gene Name | multiple endocrine neoplasia I |
Gene Type | protein-coding |
Cytoband | 11q13 |
Ensembl ID | ENSG00000133895 |
#miR regulators | 2 |
Omim ID | 131100 613733 |
Gene ontology |
GO:0000122: negative regulation of transcription from RNA polymerase II promoter GO:0000165: MAPK cascade GO:0001776: leukocyte homeostasis GO:0001933: negative regulation of protein phosphorylation GO:0002051: osteoblast fate commitment GO:0002076: osteoblast development GO:0006281: DNA repair GO:0006338: chromatin remodeling GO:0006351: transcription, DNA-dependent GO:0006367: transcription initiation from RNA polymerase II promoter GO:0006974: response to DNA damage stimulus GO:0007050: cell cycle arrest GO:0007179: transforming growth factor beta receptor signaling pathway GO:0007420: brain development GO:0008285: negative regulation of cell proliferation GO:0009411: response to UV GO:0010332: response to gamma radiation GO:0010467: gene expression GO:0045892: negative regulation of transcription, DNA-dependent GO:0030097: hemopoiesis GO:0030511: positive regulation of transforming growth factor beta receptor signaling pathway GO:0031062: positive regulation of histone methylation GO:0032092: positive regulation of protein binding GO:0032925: regulation of activin receptor signaling pathway GO:0034968: histone lysine methylation GO:0043065: positive regulation of apoptotic process GO:0043280: positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043433: negative regulation of sequence-specific DNA binding transcription factor activity GO:0045668: negative regulation of osteoblast differentiation GO:0045669: positive regulation of osteoblast differentiation GO:0045736: negative regulation of cyclin-dependent protein serine/threonine kinase activity GO:0045786: negative regulation of cell cycle GO:0045944: positive regulation of transcription from RNA polymerase II promoter GO:0046329: negative regulation of JNK cascade GO:0046621: negative regulation of organ growth GO:0048704: embryonic skeletal system morphogenesis GO:0051781: positive regulation of cell division GO:0051974: negative regulation of telomerase activity GO:0060021: palate development GO:0060135: maternal process involved in female pregnancy GO:0000785: chromatin GO:0005829: cytosol GO:0005634: nucleus GO:0005737: cytoplasm GO:0005654: nucleoplasm GO:0016363: nuclear matrix GO:0032154: cleavage furrow GO:0035097: histone methyltransferase complex GO:0043234: protein complex GO:0005515: protein binding GO:0000400: four-way junction DNA binding GO:0000403: Y-form DNA binding GO:0003682: chromatin binding GO:0003690: double-stranded DNA binding GO:0030674: protein binding, bridging GO:0044212: transcription regulatory region DNA binding GO:0018024: histone-lysine N-methyltransferase activity GO:0043565: sequence-specific DNA binding GO:0047485: protein N-terminus binding GO:0070412: R-SMAD binding |
KEGG pathways | --- |
PMID | Title | Tumor | Value |
---|---|---|---|
23137772 | A genome-wide approach to comparative oncology: high-resolution oligonucleotide aCGH of canine and human osteosarcoma pinpoints shared microaberrations. | yes | no |
title | all | all |