Results for MICB

General Information

Gene ID 4277
Gene Symbol MICB
Gene Name MHC class I polypeptide-related sequence B
Gene Type protein-coding
Cytoband 6p21.3
Ensembl ID ENSG00000204516 ENSG00000231179 ENSG00000227772 ENSG00000231372 ENSG00000238289 ENSG00000224378 ENSG00000206449 ENSG00000234218
#miR regulators 12
Omim ID 602436
Gene ontology GO:0002429: immune response-activating cell surface receptor signaling pathway
GO:0006955: immune response
GO:0006979: response to oxidative stress
GO:0019835: cytolysis
GO:0009408: response to heat
GO:0019048: modulation by virus of host morphology or physiology
GO:0019882: antigen processing and presentation
GO:0032526: response to retinoic acid
GO:0046629: gamma-delta T cell activation
GO:0050689: negative regulation of defense response to virus by host
GO:0050776: regulation of immune response
GO:0005886: plasma membrane
GO:0016021: integral to membrane
GO:0009986: cell surface
GO:0046703: natural killer cell lectin-like receptor binding
KEGG pathways 4650: Natural killer cell mediated cytotoxicity

PubMed abstracts associated with MICB

PMID Title Tumor Value
22923031 Downregulation of matrix metalloproteinase-9 mRNA by valproic acid plays a role in inhibiting the shedding of MHC class I-related molecules A and B on the surface of human osteosarcoma cells. no no
22992985 Hypoxia downregulates the expression of cell surface MICA without increasing soluble MICA in osteosarcoma cells in a HIF-1α-dependent manner. no no
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