Results for MIF

General Information

Gene ID 4282
Gene Symbol MIF
Gene Name macrophage migration inhibitory factor (glycosylation-inhibiting factor)
Gene Type protein-coding
Cytoband 22q11.23
Ensembl ID ENSG00000240972
#miR regulators 1
Omim ID 153620 604302
Gene ontology GO:0001516: prostaglandin biosynthetic process
GO:0002906: negative regulation of mature B cell apoptotic process
GO:0006954: inflammatory response
GO:0007166: cell surface receptor signaling pathway
GO:0007569: cell aging
GO:0043066: negative regulation of apoptotic process
GO:0008283: cell proliferation
GO:0010629: negative regulation of gene expression
GO:0010739: positive regulation of protein kinase A signaling cascade
GO:0019752: carboxylic acid metabolic process
GO:0030330: DNA damage response, signal transduction by p53 class mediator
GO:0030890: positive regulation of B cell proliferation
GO:0031666: positive regulation of lipopolysaccharide-mediated signaling pathway
GO:0032269: negative regulation of cellular protein metabolic process
GO:0033033: negative regulation of myeloid cell apoptotic process
GO:0033138: positive regulation of peptidyl-serine phosphorylation
GO:0042327: positive regulation of phosphorylation
GO:0043030: regulation of macrophage activation
GO:0043406: positive regulation of MAP kinase activity
GO:0043518: negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0045087: innate immune response
GO:0048146: positive regulation of fibroblast proliferation
GO:0050715: positive regulation of cytokine secretion
GO:0050731: positive regulation of peptidyl-tyrosine phosphorylation
GO:0050918: positive chemotaxis
GO:0061078: positive regulation of prostaglandin secretion involved in immune response
GO:0061081: positive regulation of myeloid leukocyte cytokine production involved in immune response
GO:0070207: protein homotrimerization
GO:0070374: positive regulation of ERK1 and ERK2 cascade
GO:0071157: negative regulation of cell cycle arrest
GO:0090238: positive regulation of arachidonic acid secretion
GO:0090344: negative regulation of cell aging
GO:1902166: negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:2000343: positive regulation of chemokine (C-X-C motif) ligand 2 production
GO:0005576: extracellular region
GO:0005615: extracellular space
GO:0005737: cytoplasm
GO:0009986: cell surface
GO:0005515: protein binding
GO:0004167: dopachrome isomerase activity
GO:0005102: receptor binding
GO:0005125: cytokine activity
GO:0005126: cytokine receptor binding
GO:0042056: chemoattractant activity
GO:0050178: phenylpyruvate tautomerase activity
KEGG pathways 350: Tyrosine metabolism
360: Phenylalanine metabolism

PubMed abstracts associated with MIF

PMID Title Tumor Value
18563508 Expression of macrophage migration inhibitory factor relates to survival in high-grade osteosarcoma. yes no
title all all