General Information
Gene ID | 4282 |
---|---|
Gene Symbol | MIF |
Gene Name | macrophage migration inhibitory factor (glycosylation-inhibiting factor) |
Gene Type | protein-coding |
Cytoband | 22q11.23 |
Ensembl ID | ENSG00000240972 |
#miR regulators | 1 |
Omim ID | 153620 604302 |
Gene ontology |
GO:0001516: prostaglandin biosynthetic process GO:0002906: negative regulation of mature B cell apoptotic process GO:0006954: inflammatory response GO:0007166: cell surface receptor signaling pathway GO:0007569: cell aging GO:0043066: negative regulation of apoptotic process GO:0008283: cell proliferation GO:0010629: negative regulation of gene expression GO:0010739: positive regulation of protein kinase A signaling cascade GO:0019752: carboxylic acid metabolic process GO:0030330: DNA damage response, signal transduction by p53 class mediator GO:0030890: positive regulation of B cell proliferation GO:0031666: positive regulation of lipopolysaccharide-mediated signaling pathway GO:0032269: negative regulation of cellular protein metabolic process GO:0033033: negative regulation of myeloid cell apoptotic process GO:0033138: positive regulation of peptidyl-serine phosphorylation GO:0042327: positive regulation of phosphorylation GO:0043030: regulation of macrophage activation GO:0043406: positive regulation of MAP kinase activity GO:0043518: negative regulation of DNA damage response, signal transduction by p53 class mediator GO:0045087: innate immune response GO:0048146: positive regulation of fibroblast proliferation GO:0050715: positive regulation of cytokine secretion GO:0050731: positive regulation of peptidyl-tyrosine phosphorylation GO:0050918: positive chemotaxis GO:0061078: positive regulation of prostaglandin secretion involved in immune response GO:0061081: positive regulation of myeloid leukocyte cytokine production involved in immune response GO:0070207: protein homotrimerization GO:0070374: positive regulation of ERK1 and ERK2 cascade GO:0071157: negative regulation of cell cycle arrest GO:0090238: positive regulation of arachidonic acid secretion GO:0090344: negative regulation of cell aging GO:1902166: negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator GO:2000343: positive regulation of chemokine (C-X-C motif) ligand 2 production GO:0005576: extracellular region GO:0005615: extracellular space GO:0005737: cytoplasm GO:0009986: cell surface GO:0005515: protein binding GO:0004167: dopachrome isomerase activity GO:0005102: receptor binding GO:0005125: cytokine activity GO:0005126: cytokine receptor binding GO:0042056: chemoattractant activity GO:0050178: phenylpyruvate tautomerase activity |
KEGG pathways |
350: Tyrosine metabolism 360: Phenylalanine metabolism |
PMID | Title | Tumor | Value |
---|---|---|---|
18563508 | Expression of macrophage migration inhibitory factor relates to survival in high-grade osteosarcoma. | yes | no |
title | all | all |