Results for MKI67

General Information

Gene ID 4288
Gene Symbol MKI67
Gene Name antigen identified by monoclonal antibody Ki-67
Gene Type protein-coding
Cytoband 10q26.2
Ensembl ID ENSG00000148773
#miR regulators 11
Omim ID 176741
Gene ontology GO:0006259: DNA metabolic process
GO:0007126: meiosis
GO:0008283: cell proliferation
GO:0031100: organ regeneration
GO:0034605: cellular response to heat
GO:0000793: condensed chromosome
GO:0000775: chromosome, centromeric region
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005730: nucleolus
GO:0005515: protein binding
GO:0005524: ATP binding
GO:0008022: protein C-terminus binding
KEGG pathways ---

PubMed abstracts associated with MKI67

PMID Title Tumor Value
8750062 Expression of p53 protein, PCNA, and Ki-67 in osteosarcomas of bone. yes no
9538120 Prognostic significance of cyclin expression in human osteosarcoma. yes yes
9685858 Association of loss of heterozygosity at the p53 locus with chemoresistance in osteosarcomas. yes yes
11155673 Preliminary observation on the correlation between nm23 expression and Ki-67 antigen with early metastasis of human osteosarcoma. yes yes
11341357 Ki-67: a proliferative marker that may predict pulmonary metastases and mortality of primary osteosarcoma. yes yes
12747978 Clinicopathological and immunohistochemical analysis of twenty-five head and neck osteosarcomas. yes no
18941626 Detection and characterization of CD133+ cancer stem cells in human solid tumours. no no
20701666 Proliferative, apoptotic and angiogenic potentials in jaws and long bones osteosarcomas: a comparative immunohistochemical study. yes no
22682017 Insulin-like growth factor type 1 receptor (IGF-1R) exclusive nuclear staining: a predictive biomarker for IGF-1R monoclonal antibody (Ab) therapy in sarcomas. yes yes
22948234 Adenovirus-mediated overexpression of BMP-9 inhibits human osteosarcoma cell growth and migration through downregulation of the PI3K/AKT pathway. no no
23527720 Knockdown of AXL receptor tyrosine kinase in osteosarcoma cells leads to decreased proliferation and increased apoptosis. yes no
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