Results for KMT2A

General Information

Gene ID 4297
Gene Symbol KMT2A
Gene Name lysine (K)-specific methyltransferase 2A
Gene Type protein-coding
Cytoband 11q23
Ensembl ID ENSG00000118058 ENSG00000267910
#miR regulators 13
Omim ID 159555 605130
Gene ontology GO:0006366: transcription from RNA polymerase II promoter
GO:0006915: apoptotic process
GO:0006461: protein complex assembly
GO:0045893: positive regulation of transcription, DNA-dependent
GO:0032411: positive regulation of transporter activity
GO:0035162: embryonic hemopoiesis
GO:0043984: histone H4-K16 acetylation
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0051568: histone H3-K4 methylation
GO:0080182: histone H3-K4 trimethylation
GO:2001040: positive regulation of cellular response to drug
GO:0005634: nucleus
GO:0035097: histone methyltransferase complex
GO:0071339: MLL1 complex
GO:0005515: protein binding
GO:0003680: AT DNA binding
GO:0003700: sequence-specific DNA binding transcription factor activity
GO:0008270: zinc ion binding
GO:0042802: identical protein binding
GO:0044212: transcription regulatory region DNA binding
GO:0042800: histone methyltransferase activity (H3-K4 specific)
GO:0042803: protein homodimerization activity
GO:0045322: unmethylated CpG binding
GO:0070577: histone acetyl-lysine binding
KEGG pathways ---

PubMed abstracts associated with KMT2A

PMID Title Tumor Value
14582536 Genomic imbalances associated with methotrexate resistance in human osteosarcoma cell lines detected by comparative genomic hybridization-based techniques. no no
19105235 Mechanisms of gene amplification and evidence of coamplification in drug-resistant human osteosarcoma cell lines. no no
title all all