General Information
| Gene ID | 4312 |
|---|---|
| Gene Symbol | MMP1 |
| Gene Name | matrix metallopeptidase 1 (interstitial collagenase) |
| Gene Type | protein-coding |
| Cytoband | 11q22.3 |
| Ensembl ID | ENSG00000196611 |
| #miR regulators | 2 |
| Omim ID | 120353 226600 |
| Gene ontology |
GO:0007596: blood coagulation GO:0006508: proteolysis GO:0019048: modulation by virus of host morphology or physiology GO:0022617: extracellular matrix disassembly GO:0030198: extracellular matrix organization GO:0030574: collagen catabolic process GO:0044267: cellular protein metabolic process GO:0050900: leukocyte migration GO:0005576: extracellular region GO:0005578: proteinaceous extracellular matrix GO:0005509: calcium ion binding GO:0004222: metalloendopeptidase activity GO:0008270: zinc ion binding |
| KEGG pathways |
3320: PPAR signaling pathway 5200: Pathways in cancer 5219: Bladder cancer 5323: Rheumatoid arthritis |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 7502710 | Regulation of plasminogen activation, matrix metalloproteinases and urokinase-type plasminogen activator-mediated extracellular matrix degradation in human osteosarcoma cell line MG63 by interleukin-1 alpha. | no | no |
| 10390144 | Transforming growth factor beta1 acts as an inducer of matrix metalloproteinase expression and activity in human bone-metastasizing cancer cells. | no | no |
| 21640141 | Phosphorylated c-Jun and Fra-1 induce matrix metalloproteinase-1 and thereby regulate invasion activity of 143B osteosarcoma cells. | no | no |
| title | all | all |