General Information
Gene ID | 4488 |
---|---|
Gene Symbol | MSX2 |
Gene Name | msh homeobox 2 |
Gene Type | protein-coding |
Cytoband | 5q35.2 |
Ensembl ID | ENSG00000120149 |
#miR regulators | 1 |
Omim ID | 123101 168500 168550 604757 |
Gene ontology |
GO:0000122: negative regulation of transcription from RNA polymerase II promoter GO:0001649: osteoblast differentiation GO:0002063: chondrocyte development GO:0002076: osteoblast development GO:0003148: outflow tract septum morphogenesis GO:0003198: epithelial to mesenchymal transition involved in endocardial cushion formation GO:0003416: endochondral bone growth GO:0043066: negative regulation of apoptotic process GO:0008285: negative regulation of cell proliferation GO:0009952: anterior/posterior pattern specification GO:0045892: negative regulation of transcription, DNA-dependent GO:0023019: signal transduction involved in regulation of gene expression GO:0030513: positive regulation of BMP signaling pathway GO:0032792: negative regulation of CREB transcription factor activity GO:0035115: embryonic forelimb morphogenesis GO:0035116: embryonic hindlimb morphogenesis GO:0035313: wound healing, spreading of epidermal cells GO:0035880: embryonic nail plate morphogenesis GO:0042640: anagen GO:0043065: positive regulation of apoptotic process GO:0045599: negative regulation of fat cell differentiation GO:0045617: negative regulation of keratinocyte differentiation GO:0045669: positive regulation of osteoblast differentiation GO:0051795: positive regulation of catagen GO:0060346: bone trabecula formation GO:0060363: cranial suture morphogenesis GO:0060364: frontal suture morphogenesis GO:0060444: branching involved in mammary gland duct morphogenesis GO:0061312: BMP signaling pathway involved in heart development GO:0070166: enamel mineralization GO:0071363: cellular response to growth factor stimulus GO:0071392: cellular response to estradiol stimulus GO:2000678: negative regulation of transcription regulatory region DNA binding GO:0005634: nucleus GO:0005737: cytoplasm GO:0005667: transcription factor complex GO:0005515: protein binding GO:0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000982: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity GO:0003712: transcription cofactor activity GO:0008134: transcription factor binding GO:0044212: transcription regulatory region DNA binding GO:0043565: sequence-specific DNA binding |
KEGG pathways | --- |
PMID | Title | Tumor | Value |
---|---|---|---|
10569470 | Expression of osteocalcin and its transcriptional regulators core-binding factor alpha 1 and MSX2 in osteoid-forming tumours. | yes | no |
title | all | all |