Results for NBN

General Information

Gene ID 4683
Gene Symbol NBN
Gene Name nibrin
Gene Type protein-coding
Cytoband 8q21
Ensembl ID ENSG00000104320
#miR regulators 11
Omim ID 251260 602667
Gene ontology GO:0000077: DNA damage checkpoint
GO:0000723: telomere maintenance
GO:0000724: double-strand break repair via homologous recombination
GO:0001832: blastocyst growth
GO:0006915: apoptotic process
GO:0006281: DNA repair
GO:0006302: double-strand break repair
GO:0007050: cell cycle arrest
GO:0007093: mitotic cell cycle checkpoint
GO:0007095: mitotic G2 DNA damage checkpoint
GO:0007126: meiosis
GO:0008283: cell proliferation
GO:0030174: regulation of DNA-dependent DNA replication initiation
GO:0030330: DNA damage response, signal transduction by p53 class mediator
GO:0031954: positive regulation of protein autophosphorylation
GO:0032508: DNA duplex unwinding
GO:0033674: positive regulation of kinase activity
GO:0045190: isotype switching
GO:0050885: neuromuscular process controlling balance
GO:0000784: nuclear chromosome, telomeric region
GO:0005634: nucleus
GO:0005654: nucleoplasm
GO:0005657: replication fork
GO:0005730: nucleolus
GO:0016605: PML body
GO:0030870: Mre11 complex
GO:0035861: site of double-strand break
GO:0042405: nuclear inclusion body
GO:0005515: protein binding
GO:0003684: damaged DNA binding
GO:0004003: ATP-dependent DNA helicase activity
GO:0008134: transcription factor binding
GO:0047485: protein N-terminus binding
KEGG pathways 3440: Homologous recombination

PubMed abstracts associated with NBN

PMID Title Tumor Value
17218778 Lack of p53 augments thymoquinone-induced apoptosis and caspase activation in human osteosarcoma cells. no no
title all all