General Information
Gene ID | 4683 |
---|---|
Gene Symbol | NBN |
Gene Name | nibrin |
Gene Type | protein-coding |
Cytoband | 8q21 |
Ensembl ID | ENSG00000104320 |
#miR regulators | 11 |
Omim ID | 251260 602667 |
Gene ontology |
GO:0000077: DNA damage checkpoint GO:0000723: telomere maintenance GO:0000724: double-strand break repair via homologous recombination GO:0001832: blastocyst growth GO:0006915: apoptotic process GO:0006281: DNA repair GO:0006302: double-strand break repair GO:0007050: cell cycle arrest GO:0007093: mitotic cell cycle checkpoint GO:0007095: mitotic G2 DNA damage checkpoint GO:0007126: meiosis GO:0008283: cell proliferation GO:0030174: regulation of DNA-dependent DNA replication initiation GO:0030330: DNA damage response, signal transduction by p53 class mediator GO:0031954: positive regulation of protein autophosphorylation GO:0032508: DNA duplex unwinding GO:0033674: positive regulation of kinase activity GO:0045190: isotype switching GO:0050885: neuromuscular process controlling balance GO:0000784: nuclear chromosome, telomeric region GO:0005634: nucleus GO:0005654: nucleoplasm GO:0005657: replication fork GO:0005730: nucleolus GO:0016605: PML body GO:0030870: Mre11 complex GO:0035861: site of double-strand break GO:0042405: nuclear inclusion body GO:0005515: protein binding GO:0003684: damaged DNA binding GO:0004003: ATP-dependent DNA helicase activity GO:0008134: transcription factor binding GO:0047485: protein N-terminus binding |
KEGG pathways |
3440: Homologous recombination |
PMID | Title | Tumor | Value |
---|---|---|---|
17218778 | Lack of p53 augments thymoquinone-induced apoptosis and caspase activation in human osteosarcoma cells. | no | no |
title | all | all |