Results for NFE2L2

General Information

Gene ID 4780
Gene Symbol NFE2L2
Gene Name nuclear factor (erythroid-derived 2)-like 2
Gene Type protein-coding
Cytoband 2q31
Ensembl ID ENSG00000116044
#miR regulators 7
Omim ID 600492
Gene ontology GO:0006366: transcription from RNA polymerase II promoter
GO:0016567: protein ubiquitination
GO:0010499: proteasomal ubiquitin-independent protein catabolic process
GO:2000379: positive regulation of reactive oxygen species metabolic process
GO:0030194: positive regulation of blood coagulation
GO:0030968: endoplasmic reticulum unfolded protein response
GO:0036003: positive regulation of transcription from RNA polymerase II promoter in response to stress
GO:0043161: proteasomal ubiquitin-dependent protein catabolic process
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0045995: regulation of embryonic development
GO:0070301: cellular response to hydrogen peroxide
GO:0071356: cellular response to tumor necrosis factor
GO:0071499: cellular response to laminar fluid shear stress
GO:1902176: negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress
GO:2000121: regulation of removal of superoxide radicals
GO:2000352: negative regulation of endothelial cell apoptotic process
GO:0005886: plasma membrane
GO:0000785: chromatin
GO:0005829: cytosol
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005813: centrosome
GO:0001102: RNA polymerase II activating transcription factor binding
GO:0003677: DNA binding
GO:0003700: sequence-specific DNA binding transcription factor activity
GO:0019904: protein domain specific binding
GO:0043565: sequence-specific DNA binding
KEGG pathways 4141: Protein processing in endoplasmic reticulum

PubMed abstracts associated with NFE2L2

PMID Title Tumor Value
23052169 Mutational and expressional analyses of NRF2 and KEAP1 in sarcomas. yes no
title all all