General Information
| Gene ID | 4791 |
|---|---|
| Gene Symbol | NFKB2 |
| Gene Name | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| Gene Type | protein-coding |
| Cytoband | 10q24 |
| Ensembl ID | ENSG00000077150 |
| #miR regulators | --- |
| Omim ID | 164012 |
| Gene ontology |
GO:0002224: toll-like receptor signaling pathway GO:0002268: follicular dendritic cell differentiation GO:0002467: germinal center formation GO:0002755: MyD88-dependent toll-like receptor signaling pathway GO:0002756: MyD88-independent toll-like receptor signaling pathway GO:0006351: transcription, DNA-dependent GO:0006355: regulation of transcription, DNA-dependent GO:0030198: extracellular matrix organization GO:0032481: positive regulation of type I interferon production GO:0034134: toll-like receptor 2 signaling pathway GO:0034138: toll-like receptor 3 signaling pathway GO:0034142: toll-like receptor 4 signaling pathway GO:0034146: toll-like receptor 5 signaling pathway GO:0034162: toll-like receptor 9 signaling pathway GO:0034166: toll-like receptor 10 signaling pathway GO:0035666: TRIF-dependent toll-like receptor signaling pathway GO:0038123: toll-like receptor TLR1:TLR2 signaling pathway GO:0038124: toll-like receptor TLR6:TLR2 signaling pathway GO:0045087: innate immune response GO:0048536: spleen development GO:0051092: positive regulation of NF-kappaB transcription factor activity GO:0005829: cytosol GO:0005634: nucleus GO:0005737: cytoplasm GO:0005654: nucleoplasm GO:0033257: Bcl3/NF-kappaB2 complex GO:0005515: protein binding GO:0003677: DNA binding GO:0003700: sequence-specific DNA binding transcription factor activity GO:0003713: transcription coactivator activity |
| KEGG pathways |
4010: MAPK signaling pathway 4380: Osteoclast differentiation 5200: Pathways in cancer |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 22147650 | Prion proteins (PRNP and PRND) are over-expressed in osteosarcoma. | yes | no |
| title | all | all |