Results for NFKBIA

General Information

Gene ID 4792
Gene Symbol NFKBIA
Gene Name nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
Gene Type protein-coding
Cytoband 14q13
Ensembl ID ENSG00000100906
#miR regulators 4
Omim ID 164008 612132
Gene ontology GO:0000060: protein import into nucleus, translocation
GO:0002224: toll-like receptor signaling pathway
GO:0002755: MyD88-dependent toll-like receptor signaling pathway
GO:0002756: MyD88-independent toll-like receptor signaling pathway
GO:0042994: cytoplasmic sequestering of transcription factor
GO:0006915: apoptotic process
GO:0007253: cytoplasmic sequestering of NF-kappaB
GO:0043066: negative regulation of apoptotic process
GO:0010745: negative regulation of macrophage derived foam cell differentiation
GO:0010875: positive regulation of cholesterol efflux
GO:0010888: negative regulation of lipid storage
GO:0019048: modulation by virus of host morphology or physiology
GO:0050852: T cell receptor signaling pathway
GO:0031663: lipopolysaccharide-mediated signaling pathway
GO:0032088: negative regulation of NF-kappaB transcription factor activity
GO:0032270: positive regulation of cellular protein metabolic process
GO:0032481: positive regulation of type I interferon production
GO:0032495: response to muramyl dipeptide
GO:0034134: toll-like receptor 2 signaling pathway
GO:0034138: toll-like receptor 3 signaling pathway
GO:0034142: toll-like receptor 4 signaling pathway
GO:0034146: toll-like receptor 5 signaling pathway
GO:0034162: toll-like receptor 9 signaling pathway
GO:0034166: toll-like receptor 10 signaling pathway
GO:0035666: TRIF-dependent toll-like receptor signaling pathway
GO:0038095: Fc-epsilon receptor signaling pathway
GO:0038123: toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124: toll-like receptor TLR6:TLR2 signaling pathway
GO:0042127: regulation of cell proliferation
GO:0042345: regulation of NF-kappaB import into nucleus
GO:0043330: response to exogenous dsRNA
GO:0043392: negative regulation of DNA binding
GO:0045087: innate immune response
GO:0045638: negative regulation of myeloid cell differentiation
GO:0045746: negative regulation of Notch signaling pathway
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0048011: neurotrophin TRK receptor signaling pathway
GO:0051092: positive regulation of NF-kappaB transcription factor activity
GO:0070417: cellular response to cold
GO:0070427: nucleotide-binding oligomerization domain containing 1 signaling pathway
GO:0070431: nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0005886: plasma membrane
GO:0005829: cytosol
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0033256: I-kappaB/NF-kappaB complex
GO:0005515: protein binding
GO:0008134: transcription factor binding
GO:0008139: nuclear localization sequence binding
GO:0042802: identical protein binding
GO:0031072: heat shock protein binding
GO:0019899: enzyme binding
GO:0031625: ubiquitin protein ligase binding
GO:0032403: protein complex binding
GO:0051059: NF-kappaB binding
KEGG pathways 4062: Chemokine signaling pathway
4210: Apoptosis
4380: Osteoclast differentiation
4620: Toll-like receptor signaling pathway
4621: NOD-like receptor signaling pathway
4622: RIG-I-like receptor signaling pathway
4623: Cytosolic DNA-sensing pathway
4660: T cell receptor signaling pathway
4662: B cell receptor signaling pathway
4722: Neurotrophin signaling pathway
4920: Adipocytokine signaling pathway
5120: Epithelial cell signaling in Helicobacter pylori infection
5131: Shigellosis
5140: Leishmaniasis
5142: Chagas disease (American trypanosomiasis)
5145: Toxoplasmosis
5160: Hepatitis C
5200: Pathways in cancer
5215: Prostate cancer
5220: Chronic myeloid leukemia
5222: Small cell lung cancer

PubMed abstracts associated with NFKBIA

PMID Title Tumor Value
17611696 Calyculin A induces apoptosis and stimulates phosphorylation of p65NF-kappaB in human osteoblastic osteosarcoma MG63 cells. no no
title all all