Results for NME1

General Information

Gene ID 4830
Gene Symbol NME1
Gene Name NME/NM23 nucleoside diphosphate kinase 1
Gene Type protein-coding
Cytoband 17q21.3
Ensembl ID ENSG00000239672
#miR regulators 1
Omim ID 156490 256700
Gene ontology GO:0002762: negative regulation of myeloid leukocyte differentiation
GO:0006183: GTP biosynthetic process
GO:0006228: UTP biosynthetic process
GO:0006241: CTP biosynthetic process
GO:0006897: endocytosis
GO:0007595: lactation
GO:0008285: negative regulation of cell proliferation
GO:0010629: negative regulation of gene expression
GO:0010976: positive regulation of neuron projection development
GO:0014075: response to amine stimulus
GO:0015949: nucleobase-containing small molecule interconversion
GO:0042981: regulation of apoptotic process
GO:0021766: hippocampus development
GO:0033574: response to testosterone stimulus
GO:0035690: cellular response to drug
GO:0043388: positive regulation of DNA binding
GO:0044281: small molecule metabolic process
GO:0050679: positive regulation of epithelial cell proliferation
GO:0051591: response to cAMP
GO:0055086: nucleobase-containing small molecule metabolic process
GO:0071333: cellular response to glucose stimulus
GO:0071398: cellular response to fatty acid
GO:0016020: membrane
GO:0005739: mitochondrion
GO:0005829: cytosol
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005813: centrosome
GO:0048471: perinuclear region of cytoplasm
GO:0005515: protein binding
GO:0000287: magnesium ion binding
GO:0000977: RNA polymerase II regulatory region sequence-specific DNA binding
GO:0003697: single-stranded DNA binding
GO:0004536: deoxyribonuclease activity
GO:0004550: nucleoside diphosphate kinase activity
GO:0005524: ATP binding
GO:0005525: GTP binding
GO:0042802: identical protein binding
GO:0019215: intermediate filament binding
GO:0019901: protein kinase binding
GO:0043015: gamma-tubulin binding
GO:0043024: ribosomal small subunit binding
KEGG pathways 230: Purine metabolism
240: Pyrimidine metabolism
1100: Metabolic pathways

PubMed abstracts associated with NME1

PMID Title Tumor Value
7593131 Immunohistochemical analysis of nm23 protein expression in malignant bone tumors. yes yes
10872665 Comparison of histological changes and changes in nm23 and c-MET expression between primary and metastatic sites in osteosarcoma: a clinicopathologic and immunohistochemical study. yes yes
11103961 Expression of nm23 protein in human osteosarcoma in relationship with early metastasis. yes no
11155673 Preliminary observation on the correlation between nm23 expression and Ki-67 antigen with early metastasis of human osteosarcoma. yes yes
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