Results for NOS2

General Information

Gene ID 4843
Gene Symbol NOS2
Gene Name nitric oxide synthase 2, inducible
Gene Type protein-coding
Cytoband 17q11.2-q12
Ensembl ID ENSG00000007171
#miR regulators 7
Omim ID 145500 163730 611162
Gene ontology GO:0001666: response to hypoxia
GO:0001912: positive regulation of leukocyte mediated cytotoxicity
GO:0002227: innate immune response in mucosa
GO:0042742: defense response to bacterium
GO:0007596: blood coagulation
GO:0006527: arginine catabolic process
GO:0006801: superoxide metabolic process
GO:0006809: nitric oxide biosynthetic process
GO:0006954: inflammatory response
GO:0007263: nitric oxide mediated signal transduction
GO:0050796: regulation of insulin secretion
GO:0050829: defense response to Gram-negative bacterium
GO:0045909: positive regulation of vasodilation
GO:0009617: response to bacterium
GO:0010629: negative regulation of gene expression
GO:0018119: peptidyl-cysteine S-nitrosylation
GO:0031284: positive regulation of guanylate cyclase activity
GO:0042127: regulation of cell proliferation
GO:0042177: negative regulation of protein catabolic process
GO:0043457: regulation of cellular respiration
GO:0045776: negative regulation of blood pressure
GO:0051701: interaction with host
GO:0051712: positive regulation of killing of cells of other organism
GO:0071222: cellular response to lipopolysaccharide
GO:0071346: cellular response to interferon-gamma
GO:0090382: phagosome maturation
GO:0005622: intracellular
GO:0005829: cytosol
GO:0005777: peroxisome
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0030863: cortical cytoskeleton
GO:0048471: perinuclear region of cytoplasm
GO:0005515: protein binding
GO:0003958: NADPH-hemoprotein reductase activity
GO:0005102: receptor binding
GO:0004517: nitric-oxide synthase activity
GO:0005506: iron ion binding
GO:0005516: calmodulin binding
GO:0010181: FMN binding
GO:0020037: heme binding
GO:0034617: tetrahydrobiopterin binding
GO:0034618: arginine binding
GO:0042803: protein homodimerization activity
GO:0050660: flavin adenine dinucleotide binding
GO:0050661: NADP binding
KEGG pathways 330: Arginine and proline metabolism
1100: Metabolic pathways
4020: Calcium signaling pathway
4146: Peroxisome
5140: Leishmaniasis
5142: Chagas disease (American trypanosomiasis)
5145: Toxoplasmosis
5146: Amoebiasis
5200: Pathways in cancer
5222: Small cell lung cancer

PubMed abstracts associated with NOS2

PMID Title Tumor Value
17391929 Expression and pathological relevance of inducible nitric oxide synthase in osteosarcoma of the jaws. yes yes
title all all