Results for NRAS

General Information

Gene ID 4893
Gene Symbol NRAS
Gene Name neuroblastoma RAS viral (v-ras) oncogene homolog
Gene Type protein-coding
Cytoband 1p13.2
Ensembl ID ENSG00000213281
#miR regulators 15
Omim ID 114500 162900 164790 188470 613224 614470
Gene ontology GO:0000165: MAPK cascade
GO:0000186: activation of MAPKK activity
GO:0030036: actin cytoskeleton organization
GO:0007596: blood coagulation
GO:0007173: epidermal growth factor receptor signaling pathway
GO:0007264: small GTPase mediated signal transduction
GO:0007265: Ras protein signal transduction
GO:0007411: axon guidance
GO:0008284: positive regulation of cell proliferation
GO:0008286: insulin receptor signaling pathway
GO:0008542: visual learning
GO:0008543: fibroblast growth factor receptor signaling pathway
GO:0032228: regulation of synaptic transmission, GABAergic
GO:0035022: positive regulation of Rac protein signal transduction
GO:0038095: Fc-epsilon receptor signaling pathway
GO:0043524: negative regulation of neuron apoptotic process
GO:0045087: innate immune response
GO:0048011: neurotrophin TRK receptor signaling pathway
GO:0048169: regulation of long-term neuronal synaptic plasticity
GO:0050900: leukocyte migration
GO:0051146: striated muscle cell differentiation
GO:0005886: plasma membrane
GO:0000139: Golgi membrane
GO:0003924: GTPase activity
GO:0005525: GTP binding
KEGG pathways 4010: MAPK signaling pathway
4012: ErbB signaling pathway
4062: Chemokine signaling pathway
4360: Axon guidance
4370: VEGF signaling pathway
4530: Tight junction
4540: Gap junction
4650: Natural killer cell mediated cytotoxicity
4660: T cell receptor signaling pathway
4662: B cell receptor signaling pathway
4664: Fc epsilon RI signaling pathway
4720: Long-term potentiation
4722: Neurotrophin signaling pathway
4730: Long-term depression
4810: Regulation of actin cytoskeleton
4910: Insulin signaling pathway
4912: GnRH signaling pathway
4916: Melanogenesis
5160: Hepatitis C
5200: Pathways in cancer
5211: Renal cell carcinoma
5213: Endometrial cancer
5214: Glioma
5215: Prostate cancer
5216: Thyroid cancer
5218: Melanoma
5219: Bladder cancer
5220: Chronic myeloid leukemia
5221: Acute myeloid leukemia
5223: Non-small cell lung cancer

PubMed abstracts associated with NRAS

PMID Title Tumor Value
7850751 Mutational activation of ras genes is absent in pediatric osteosarcoma. yes no
20406948 Driven to death: inhibition of farnesylation increases Ras activity in osteosarcoma and promotes growth arrest and cell death. no no
20592496 Arsenic trioxide inhibits osteosarcoma cell invasiveness via MAPK signaling pathway. no no
title all all