General Information
Gene ID | 5025 |
---|---|
Gene Symbol | P2RX4 |
Gene Name | purinergic receptor P2X, ligand-gated ion channel, 4 |
Gene Type | protein-coding |
Cytoband | 12q24.32 |
Ensembl ID | ENSG00000135124 |
#miR regulators | 8 |
Omim ID | 600846 |
Gene ontology |
GO:0001894: tissue homeostasis GO:0002028: regulation of sodium ion transport GO:0007165: signal transduction GO:0006810: transport GO:0008217: regulation of blood pressure GO:0010524: positive regulation of calcium ion transport into cytosol GO:0010614: negative regulation of cardiac muscle hypertrophy GO:0019233: sensory perception of pain GO:0032308: positive regulation of prostaglandin secretion GO:0033198: response to ATP GO:0034405: response to fluid shear stress GO:0035590: purinergic nucleotide receptor signaling pathway GO:0042118: endothelial cell activation GO:0045429: positive regulation of nitric oxide biosynthetic process GO:0050850: positive regulation of calcium-mediated signaling GO:0051899: membrane depolarization GO:0051928: positive regulation of calcium ion transport GO:0055117: regulation of cardiac muscle contraction GO:0055119: relaxation of cardiac muscle GO:0097190: apoptotic signaling pathway GO:0005886: plasma membrane GO:0016020: membrane GO:0005887: integral to plasma membrane GO:0030054: cell junction GO:0048471: perinuclear region of cytoplasm GO:0001614: purinergic nucleotide receptor activity GO:0005102: receptor binding GO:0004931: extracellular ATP-gated cation channel activity GO:0005507: copper ion binding GO:0005524: ATP binding GO:0008270: zinc ion binding GO:0042803: protein homodimerization activity GO:0045296: cadherin binding |
KEGG pathways |
4020: Calcium signaling pathway 4080: Neuroactive ligand-receptor interaction |
PMID | Title | Tumor | Value |
---|---|---|---|
20114058 | Butyl benzyl phthalate suppresses the ATP-induced cell proliferation in human osteosarcoma HOS cells. | no | no |
title | all | all |