Results for P2RX7

General Information

Gene ID 5027
Gene Symbol P2RX7
Gene Name purinergic receptor P2X, ligand-gated ion channel, 7
Gene Type protein-coding
Cytoband 12q24
Ensembl ID ENSG00000089041
#miR regulators 8
Omim ID 602566
Gene ontology GO:0000187: activation of MAPK activity
GO:0000902: cell morphogenesis
GO:0001845: phagolysosome assembly
GO:0001916: positive regulation of T cell mediated cytotoxicity
GO:0002028: regulation of sodium ion transport
GO:0006468: protein phosphorylation
GO:0006509: membrane protein ectodomain proteolysis
GO:0016485: protein processing
GO:0006649: phospholipid transfer to membrane
GO:0072593: reactive oxygen species metabolic process
GO:0006884: cell volume homeostasis
GO:0006900: membrane budding
GO:0009612: response to mechanical stimulus
GO:0006954: inflammatory response
GO:0007005: mitochondrion organization
GO:0007009: plasma membrane organization
GO:0007166: cell surface receptor signaling pathway
GO:0019835: cytolysis
GO:0050830: defense response to Gram-positive bacterium
GO:0042493: response to drug
GO:0010043: response to zinc ion
GO:0010524: positive regulation of calcium ion transport into cytosol
GO:0014049: positive regulation of glutamate secretion
GO:0014054: positive regulation of gamma-aminobutyric acid secretion
GO:0046931: pore complex assembly
GO:0016079: synaptic vesicle exocytosis
GO:0019228: regulation of action potential in neuron
GO:0019233: sensory perception of pain
GO:0030501: positive regulation of bone mineralization
GO:0031668: cellular response to extracellular stimulus
GO:0032060: bleb assembly
GO:0032308: positive regulation of prostaglandin secretion
GO:0032496: response to lipopolysaccharide
GO:0032755: positive regulation of interleukin-6 production
GO:0032963: collagen metabolic process
GO:0033198: response to ATP
GO:0034405: response to fluid shear stress
GO:0035590: purinergic nucleotide receptor signaling pathway
GO:0035872: nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
GO:0042098: T cell proliferation
GO:0043029: T cell homeostasis
GO:0043065: positive regulation of apoptotic process
GO:0043132: NAD transport
GO:0043409: negative regulation of MAPK cascade
GO:0044254: multicellular organismal protein catabolic process
GO:0045087: innate immune response
GO:0045332: phospholipid translocation
GO:0045779: negative regulation of bone resorption
GO:0045919: positive regulation of cytolysis
GO:0046513: ceramide biosynthetic process
GO:0048705: skeletal system morphogenesis
GO:0048873: homeostasis of number of cells within a tissue
GO:0050717: positive regulation of interleukin-1 alpha secretion
GO:0050718: positive regulation of interleukin-1 beta secretion
GO:0051209: release of sequestered calcium ion into cytosol
GO:0051259: protein oligomerization
GO:0051495: positive regulation of cytoskeleton organization
GO:0051592: response to calcium ion
GO:0051602: response to electrical stimulus
GO:0051709: regulation of killing of cells of other organism
GO:0051899: membrane depolarization
GO:0051901: positive regulation of mitochondrial depolarization
GO:0097190: apoptotic signaling pathway
GO:0005886: plasma membrane
GO:0016020: membrane
GO:0005887: integral to plasma membrane
GO:0005639: integral to nuclear inner membrane
GO:0005737: cytoplasm
GO:0005911: cell-cell junction
GO:0009897: external side of plasma membrane
GO:0031594: neuromuscular junction
GO:0032059: bleb
GO:0043025: neuronal cell body
GO:0043195: terminal bouton
GO:0043234: protein complex
GO:0045121: membrane raft
GO:0000287: magnesium ion binding
GO:0001530: lipopolysaccharide binding
GO:0001614: purinergic nucleotide receptor activity
GO:0005102: receptor binding
GO:0004931: extracellular ATP-gated cation channel activity
GO:0005507: copper ion binding
GO:0005524: ATP binding
GO:0008270: zinc ion binding
GO:0042803: protein homodimerization activity
GO:0097110: scaffold protein binding
KEGG pathways 4020: Calcium signaling pathway
4080: Neuroactive ligand-receptor interaction

PubMed abstracts associated with P2RX7

PMID Title Tumor Value
20114058 Butyl benzyl phthalate suppresses the ATP-induced cell proliferation in human osteosarcoma HOS cells. no no
title all all