General Information
Gene ID | 5027 |
---|---|
Gene Symbol | P2RX7 |
Gene Name | purinergic receptor P2X, ligand-gated ion channel, 7 |
Gene Type | protein-coding |
Cytoband | 12q24 |
Ensembl ID | ENSG00000089041 |
#miR regulators | 8 |
Omim ID | 602566 |
Gene ontology |
GO:0000187: activation of MAPK activity GO:0000902: cell morphogenesis GO:0001845: phagolysosome assembly GO:0001916: positive regulation of T cell mediated cytotoxicity GO:0002028: regulation of sodium ion transport GO:0006468: protein phosphorylation GO:0006509: membrane protein ectodomain proteolysis GO:0016485: protein processing GO:0006649: phospholipid transfer to membrane GO:0072593: reactive oxygen species metabolic process GO:0006884: cell volume homeostasis GO:0006900: membrane budding GO:0009612: response to mechanical stimulus GO:0006954: inflammatory response GO:0007005: mitochondrion organization GO:0007009: plasma membrane organization GO:0007166: cell surface receptor signaling pathway GO:0019835: cytolysis GO:0050830: defense response to Gram-positive bacterium GO:0042493: response to drug GO:0010043: response to zinc ion GO:0010524: positive regulation of calcium ion transport into cytosol GO:0014049: positive regulation of glutamate secretion GO:0014054: positive regulation of gamma-aminobutyric acid secretion GO:0046931: pore complex assembly GO:0016079: synaptic vesicle exocytosis GO:0019228: regulation of action potential in neuron GO:0019233: sensory perception of pain GO:0030501: positive regulation of bone mineralization GO:0031668: cellular response to extracellular stimulus GO:0032060: bleb assembly GO:0032308: positive regulation of prostaglandin secretion GO:0032496: response to lipopolysaccharide GO:0032755: positive regulation of interleukin-6 production GO:0032963: collagen metabolic process GO:0033198: response to ATP GO:0034405: response to fluid shear stress GO:0035590: purinergic nucleotide receptor signaling pathway GO:0035872: nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway GO:0042098: T cell proliferation GO:0043029: T cell homeostasis GO:0043065: positive regulation of apoptotic process GO:0043132: NAD transport GO:0043409: negative regulation of MAPK cascade GO:0044254: multicellular organismal protein catabolic process GO:0045087: innate immune response GO:0045332: phospholipid translocation GO:0045779: negative regulation of bone resorption GO:0045919: positive regulation of cytolysis GO:0046513: ceramide biosynthetic process GO:0048705: skeletal system morphogenesis GO:0048873: homeostasis of number of cells within a tissue GO:0050717: positive regulation of interleukin-1 alpha secretion GO:0050718: positive regulation of interleukin-1 beta secretion GO:0051209: release of sequestered calcium ion into cytosol GO:0051259: protein oligomerization GO:0051495: positive regulation of cytoskeleton organization GO:0051592: response to calcium ion GO:0051602: response to electrical stimulus GO:0051709: regulation of killing of cells of other organism GO:0051899: membrane depolarization GO:0051901: positive regulation of mitochondrial depolarization GO:0097190: apoptotic signaling pathway GO:0005886: plasma membrane GO:0016020: membrane GO:0005887: integral to plasma membrane GO:0005639: integral to nuclear inner membrane GO:0005737: cytoplasm GO:0005911: cell-cell junction GO:0009897: external side of plasma membrane GO:0031594: neuromuscular junction GO:0032059: bleb GO:0043025: neuronal cell body GO:0043195: terminal bouton GO:0043234: protein complex GO:0045121: membrane raft GO:0000287: magnesium ion binding GO:0001530: lipopolysaccharide binding GO:0001614: purinergic nucleotide receptor activity GO:0005102: receptor binding GO:0004931: extracellular ATP-gated cation channel activity GO:0005507: copper ion binding GO:0005524: ATP binding GO:0008270: zinc ion binding GO:0042803: protein homodimerization activity GO:0097110: scaffold protein binding |
KEGG pathways |
4020: Calcium signaling pathway 4080: Neuroactive ligand-receptor interaction |
PMID | Title | Tumor | Value |
---|---|---|---|
20114058 | Butyl benzyl phthalate suppresses the ATP-induced cell proliferation in human osteosarcoma HOS cells. | no | no |
title | all | all |