Results for PDE3A

General Information

Gene ID 5139
Gene Symbol PDE3A
Gene Name phosphodiesterase 3A, cGMP-inhibited
Gene Type protein-coding
Cytoband 12p12
Ensembl ID ENSG00000172572
#miR regulators 4
Omim ID 123805
Gene ontology GO:0001556: oocyte maturation
GO:0007596: blood coagulation
GO:0006198: cAMP catabolic process
GO:0006629: lipid metabolic process
GO:0043066: negative regulation of apoptotic process
GO:0042493: response to drug
GO:0016101: diterpenoid metabolic process
GO:0019933: cAMP-mediated signaling
GO:0019934: cGMP-mediated signaling
GO:0040020: regulation of meiosis
GO:0043116: negative regulation of vascular permeability
GO:0043117: positive regulation of vascular permeability
GO:0051591: response to cAMP
GO:0060282: positive regulation of oocyte development
GO:0071321: cellular response to cGMP
GO:0071560: cellular response to transforming growth factor beta stimulus
GO:0016021: integral to membrane
GO:0005829: cytosol
GO:0004115: 3',5'-cyclic-AMP phosphodiesterase activity
GO:0004119: cGMP-inhibited cyclic-nucleotide phosphodiesterase activity
GO:0046872: metal ion binding
GO:0030552: cAMP binding
KEGG pathways 230: Purine metabolism
4910: Insulin signaling pathway
4914: Progesterone-mediated oocyte maturation

PubMed abstracts associated with PDE3A

PMID Title Tumor Value
15627479 Dexamethasone down-regulates cAMP-phosphodiesterase in human osteosarcoma cells. no no
16010295 Cyclic nucleotide phosphodiesterases (PDEs) in human osteoblastic cells; the effect of PDE inhibition on cAMP accumulation. no no
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