General Information
| Gene ID | 5139 |
|---|---|
| Gene Symbol | PDE3A |
| Gene Name | phosphodiesterase 3A, cGMP-inhibited |
| Gene Type | protein-coding |
| Cytoband | 12p12 |
| Ensembl ID | ENSG00000172572 |
| #miR regulators | 4 |
| Omim ID | 123805 |
| Gene ontology |
GO:0001556: oocyte maturation GO:0007596: blood coagulation GO:0006198: cAMP catabolic process GO:0006629: lipid metabolic process GO:0043066: negative regulation of apoptotic process GO:0042493: response to drug GO:0016101: diterpenoid metabolic process GO:0019933: cAMP-mediated signaling GO:0019934: cGMP-mediated signaling GO:0040020: regulation of meiosis GO:0043116: negative regulation of vascular permeability GO:0043117: positive regulation of vascular permeability GO:0051591: response to cAMP GO:0060282: positive regulation of oocyte development GO:0071321: cellular response to cGMP GO:0071560: cellular response to transforming growth factor beta stimulus GO:0016021: integral to membrane GO:0005829: cytosol GO:0004115: 3',5'-cyclic-AMP phosphodiesterase activity GO:0004119: cGMP-inhibited cyclic-nucleotide phosphodiesterase activity GO:0046872: metal ion binding GO:0030552: cAMP binding |
| KEGG pathways |
230: Purine metabolism 4910: Insulin signaling pathway 4914: Progesterone-mediated oocyte maturation |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 15627479 | Dexamethasone down-regulates cAMP-phosphodiesterase in human osteosarcoma cells. | no | no |
| 16010295 | Cyclic nucleotide phosphodiesterases (PDEs) in human osteoblastic cells; the effect of PDE inhibition on cAMP accumulation. | no | no |
| title | all | all |