Results for PDE4D

General Information

Gene ID 5144
Gene Symbol PDE4D
Gene Name phosphodiesterase 4D, cAMP-specific
Gene Type protein-coding
Cytoband 5q12
Ensembl ID ENSG00000113448
#miR regulators 10
Omim ID 600129 606799 614613
Gene ontology GO:0002027: regulation of heart rate
GO:0006198: cAMP catabolic process
GO:0006939: smooth muscle contraction
GO:0007568: aging
GO:0010469: regulation of receptor activity
GO:0010880: regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0019933: cAMP-mediated signaling
GO:0050852: T cell receptor signaling pathway
GO:0030593: neutrophil chemotaxis
GO:0032729: positive regulation of interferon-gamma production
GO:0032743: positive regulation of interleukin-2 production
GO:0032754: positive regulation of interleukin-5 production
GO:0033137: negative regulation of peptidyl-serine phosphorylation
GO:0035264: multicellular organism growth
GO:0045822: negative regulation of heart contraction
GO:0060314: regulation of ryanodine-sensitive calcium-release channel activity
GO:0061028: establishment of endothelial barrier
GO:0071222: cellular response to lipopolysaccharide
GO:0071320: cellular response to cAMP
GO:0071872: cellular response to epinephrine stimulus
GO:0071875: adrenergic receptor signaling pathway
GO:0086004: regulation of cardiac muscle cell contraction
GO:0086024: adrenergic receptor signaling pathway involved in positive regulation of heart rate
GO:1901844: regulation of cell communication by electrical coupling involved in cardiac conduction
GO:1901898: negative regulation of relaxation of cardiac muscle
GO:0016020: membrane
GO:0005829: cytosol
GO:0005815: microtubule organizing center
GO:0005891: voltage-gated calcium channel complex
GO:0034704: calcium channel complex
GO:0004114: 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004115: 3',5'-cyclic-AMP phosphodiesterase activity
GO:0046872: metal ion binding
GO:0008144: drug binding
GO:0019899: enzyme binding
GO:0030552: cAMP binding
GO:0031625: ubiquitin protein ligase binding
GO:0031698: beta-2 adrenergic receptor binding
GO:0044325: ion channel binding
GO:0051117: ATPase binding
GO:0097110: scaffold protein binding
KEGG pathways 230: Purine metabolism

PubMed abstracts associated with PDE4D

PMID Title Tumor Value
15627479 Dexamethasone down-regulates cAMP-phosphodiesterase in human osteosarcoma cells. no no
title all all