General Information
Gene ID | 5170 |
---|---|
Gene Symbol | PDPK1 |
Gene Name | 3-phosphoinositide dependent protein kinase-1 |
Gene Type | protein-coding |
Cytoband | 16p13.3 |
Ensembl ID | ENSG00000140992 |
#miR regulators | 11 |
Omim ID | 605213 |
Gene ontology |
GO:0003323: type B pancreatic cell development GO:0030036: actin cytoskeleton organization GO:0007596: blood coagulation GO:0035556: intracellular signal transduction GO:0006351: transcription, DNA-dependent GO:0006355: regulation of transcription, DNA-dependent GO:0006468: protein phosphorylation GO:0006469: negative regulation of protein kinase activity GO:0006972: hyperosmotic response GO:0007173: epidermal growth factor receptor signaling pathway GO:0007268: synaptic transmission GO:0008286: insulin receptor signaling pathway GO:0008543: fibroblast growth factor receptor signaling pathway GO:0010594: regulation of endothelial cell migration GO:0010667: negative regulation of cardiac muscle cell apoptotic process GO:0018107: peptidyl-threonine phosphorylation GO:0048015: phosphatidylinositol-mediated signaling GO:0050852: T cell receptor signaling pathway GO:0030168: platelet activation GO:0030512: negative regulation of transforming growth factor beta receptor signaling pathway GO:0031295: T cell costimulation GO:0032148: activation of protein kinase B activity GO:0032869: cellular response to insulin stimulus GO:0034122: negative regulation of toll-like receptor signaling pathway GO:0038095: Fc-epsilon receptor signaling pathway GO:0043122: regulation of I-kappaB kinase/NF-kappaB cascade GO:0043304: regulation of mast cell degranulation GO:0045087: innate immune response GO:0046777: protein autophosphorylation GO:0048011: neurotrophin TRK receptor signaling pathway GO:0048041: focal adhesion assembly GO:0090004: positive regulation of establishment of protein localization to plasma membrane GO:0097191: extrinsic apoptotic signaling pathway GO:0005886: plasma membrane GO:0016020: membrane GO:0005829: cytosol GO:0005737: cytoplasm GO:0005654: nucleoplasm GO:0005925: focal adhesion GO:0016023: cytoplasmic membrane-bounded vesicle GO:0005515: protein binding GO:0004674: protein serine/threonine kinase activity GO:0004676: 3-phosphoinositide-dependent protein kinase activity GO:0005158: insulin receptor binding GO:0005524: ATP binding GO:0016301: kinase activity GO:0019901: protein kinase binding |
KEGG pathways |
3320: PPAR signaling pathway 4150: mTOR signaling pathway 4510: Focal adhesion 4910: Insulin signaling pathway 4960: Aldosterone-regulated sodium reabsorption 5213: Endometrial cancer 5215: Prostate cancer 5223: Non-small cell lung cancer |
PMID | Title | Tumor | Value |
---|---|---|---|
15547696 | Sensitization of multidrug resistant human ostesarcoma cells to Apo2 Ligand/TRAIL-induced apoptosis by inhibition of the Akt/PKB kinase. | no | no |
title | all | all |