Results for PHB

General Information

Gene ID 5245
Gene Symbol PHB
Gene Name prohibitin
Gene Type protein-coding
Cytoband 17q21
Ensembl ID ENSG00000167085
#miR regulators 6
Omim ID 114480 176705
Gene ontology GO:0006260: DNA replication
GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0007165: signal transduction
GO:0006355: regulation of transcription, DNA-dependent
GO:0008285: negative regulation of cell proliferation
GO:0010944: negative regulation of transcription by competitive promoter binding
GO:0042981: regulation of apoptotic process
GO:0045893: positive regulation of transcription, DNA-dependent
GO:0045892: negative regulation of transcription, DNA-dependent
GO:0016575: histone deacetylation
GO:0030308: negative regulation of cell growth
GO:0050847: progesterone receptor signaling pathway
GO:0060766: negative regulation of androgen receptor signaling pathway
GO:0071354: cellular response to interleukin-6
GO:0071897: DNA biosynthetic process
GO:2000323: negative regulation of glucocorticoid receptor signaling pathway
GO:0005739: mitochondrion
GO:0005887: integral to plasma membrane
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005654: nucleoplasm
GO:0005743: mitochondrial inner membrane
GO:0005515: protein binding
GO:0000981: sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0044212: transcription regulatory region DNA binding
GO:0042826: histone deacetylase binding
KEGG pathways ---

PubMed abstracts associated with PHB

PMID Title Tumor Value
17660802 Prognostic significance of drug-regulated genes in high-grade osteosarcoma. yes yes
19212829 Comparative proteomic analysis of osteosarcoma cell and human primary cultured osteoblastic cell. yes no
title all all