Results for PIK3R1

General Information

Gene ID 5295
Gene Symbol PIK3R1
Gene Name phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
Gene Type protein-coding
Cytoband 5q13.1
Ensembl ID ENSG00000145675
#miR regulators 13
Omim ID 171833 269880 615214
Gene ontology GO:0001953: negative regulation of cell-matrix adhesion
GO:0007596: blood coagulation
GO:0006468: protein phosphorylation
GO:0006644: phospholipid metabolic process
GO:0006661: phosphatidylinositol biosynthetic process
GO:0007173: epidermal growth factor receptor signaling pathway
GO:0043066: negative regulation of apoptotic process
GO:0008286: insulin receptor signaling pathway
GO:0008543: fibroblast growth factor receptor signaling pathway
GO:0014065: phosphatidylinositol 3-kinase cascade
GO:0046326: positive regulation of glucose import
GO:0019048: modulation by virus of host morphology or physiology
GO:0048015: phosphatidylinositol-mediated signaling
GO:0050852: T cell receptor signaling pathway
GO:0030168: platelet activation
GO:0030183: B cell differentiation
GO:0030335: positive regulation of cell migration
GO:0031295: T cell costimulation
GO:0034644: cellular response to UV
GO:0038095: Fc-epsilon receptor signaling pathway
GO:0038096: Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0043065: positive regulation of apoptotic process
GO:0043551: regulation of phosphatidylinositol 3-kinase activity
GO:0044281: small molecule metabolic process
GO:0045087: innate immune response
GO:0045671: negative regulation of osteoclast differentiation
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0046854: phosphatidylinositol phosphorylation
GO:0048009: insulin-like growth factor receptor signaling pathway
GO:0048011: neurotrophin TRK receptor signaling pathway
GO:0050900: leukocyte migration
GO:0051531: NFAT protein import into nucleus
GO:0060396: growth hormone receptor signaling pathway
GO:0090004: positive regulation of establishment of protein localization to plasma membrane
GO:0005886: plasma membrane
GO:0005829: cytosol
GO:0005942: phosphatidylinositol 3-kinase complex
GO:0005943: 1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex
GO:0005515: protein binding
GO:0043125: ErbB-3 class receptor binding
GO:0005068: transmembrane receptor protein tyrosine kinase adaptor activity
GO:0005158: insulin receptor binding
GO:0005159: insulin-like growth factor receptor binding
GO:0005168: neurotrophin TRKA receptor binding
GO:0005545: 1-phosphatidylinositol binding
GO:0019903: protein phosphatase binding
GO:0035014: phosphatidylinositol 3-kinase regulator activity
GO:0043548: phosphatidylinositol 3-kinase binding
GO:0043559: insulin binding
GO:0043560: insulin receptor substrate binding
KEGG pathways 4012: ErbB signaling pathway
4062: Chemokine signaling pathway
4070: Phosphatidylinositol signaling system
4150: mTOR signaling pathway
4210: Apoptosis
4370: VEGF signaling pathway
4380: Osteoclast differentiation
4510: Focal adhesion
4620: Toll-like receptor signaling pathway
4630: Jak-STAT signaling pathway
4650: Natural killer cell mediated cytotoxicity
4660: T cell receptor signaling pathway
4662: B cell receptor signaling pathway
4664: Fc epsilon RI signaling pathway
4666: Fc gamma R-mediated phagocytosis
4670: Leukocyte transendothelial migration
4722: Neurotrophin signaling pathway
4810: Regulation of actin cytoskeleton
4910: Insulin signaling pathway
4914: Progesterone-mediated oocyte maturation
4930: Type II diabetes mellitus
4960: Aldosterone-regulated sodium reabsorption
4973: Carbohydrate digestion and absorption
5100: Bacterial invasion of epithelial cells
5142: Chagas disease (American trypanosomiasis)
5145: Toxoplasmosis
5146: Amoebiasis
5160: Hepatitis C
5200: Pathways in cancer
5210: Colorectal cancer
5211: Renal cell carcinoma
5212: Pancreatic cancer
5213: Endometrial cancer
5214: Glioma
5215: Prostate cancer
5218: Melanoma
5220: Chronic myeloid leukemia
5221: Acute myeloid leukemia
5222: Small cell lung cancer
5223: Non-small cell lung cancer

PubMed abstracts associated with PIK3R1

PMID Title Tumor Value
23133552 Modulation of the osteosarcoma expression phenotype by microRNAs. yes no
title all all