Results for PLA2G2A

General Information

Gene ID 5320
Gene Symbol PLA2G2A
Gene Name phospholipase A2, group IIA (platelets, synovial fluid)
Gene Type protein-coding
Cytoband 1p35
Ensembl ID ENSG00000188257
#miR regulators 2
Omim ID 114500 172411
Gene ontology GO:0006644: phospholipid metabolic process
GO:0006654: phosphatidic acid biosynthetic process
GO:0050830: defense response to Gram-positive bacterium
GO:0010744: positive regulation of macrophage derived foam cell differentiation
GO:0016042: lipid catabolic process
GO:0034374: low-density lipoprotein particle remodeling
GO:0036148: phosphatidylglycerol acyl-chain remodeling
GO:0036149: phosphatidylinositol acyl-chain remodeling
GO:0036150: phosphatidylserine acyl-chain remodeling
GO:0036151: phosphatidylcholine acyl-chain remodeling
GO:0036152: phosphatidylethanolamine acyl-chain remodeling
GO:0044281: small molecule metabolic process
GO:0046473: phosphatidic acid metabolic process
GO:0046474: glycerophospholipid biosynthetic process
GO:0050729: positive regulation of inflammatory response
GO:0005576: extracellular region
GO:0005783: endoplasmic reticulum
GO:0005615: extracellular space
GO:0005789: endoplasmic reticulum membrane
GO:0030141: secretory granule
GO:0005509: calcium ion binding
GO:0004623: phospholipase A2 activity
GO:0047498: calcium-dependent phospholipase A2 activity
GO:0005543: phospholipid binding
KEGG pathways 564: Glycerophospholipid metabolism
565: Ether lipid metabolism
590: Arachidonic acid metabolism
591: Linoleic acid metabolism
592: alpha-Linolenic acid metabolism
1100: Metabolic pathways
4010: MAPK signaling pathway
4270: Vascular smooth muscle contraction
4370: VEGF signaling pathway
4664: Fc epsilon RI signaling pathway
4730: Long-term depression
4912: GnRH signaling pathway
4972: Pancreatic secretion
4975: Fat digestion and absorption
5145: Toxoplasmosis

PubMed abstracts associated with PLA2G2A

PMID Title Tumor Value
15753370 An expression signature classifies chemotherapy-resistant pediatric osteosarcoma. yes no
title all all