Results for PLAUR

General Information

Gene ID 5329
Gene Symbol PLAUR
Gene Name plasminogen activator, urokinase receptor
Gene Type protein-coding
Cytoband 19q13
Ensembl ID ENSG00000011422
#miR regulators 5
Omim ID 173391
Gene ontology GO:0007596: blood coagulation
GO:0007165: signal transduction
GO:0006501: C-terminal protein lipidation
GO:0006928: cellular component movement
GO:0006935: chemotaxis
GO:0016255: attachment of GPI anchor to protein
GO:0030162: regulation of proteolysis
GO:0042730: fibrinolysis
GO:0043687: post-translational protein modification
GO:0044267: cellular protein metabolic process
GO:0005886: plasma membrane
GO:0016021: integral to membrane
GO:0019898: extrinsic to membrane
GO:0005576: extracellular region
GO:0005887: integral to plasma membrane
GO:0005788: endoplasmic reticulum lumen
GO:0005789: endoplasmic reticulum membrane
GO:0009986: cell surface
GO:0031225: anchored to membrane
GO:0005515: protein binding
GO:0004872: receptor activity
GO:0019899: enzyme binding
GO:0030377: U-plasminogen activator receptor activity
KEGG pathways 4610: Complement and coagulation cascades

PubMed abstracts associated with PLAUR

PMID Title Tumor Value
8391387 Overexpression of urokinase receptor increases matrix invasion without altering cell migration in a human osteosarcoma cell line. no no
10086509 Protease expression in dedifferentiated parosteal osteosarcoma. yes no
10807968 Effect of hyperthermia on the viability and the fibrinolytic potential of human cancer cell lines. no no
15095405 IGF-1 receptor contributes to the malignant phenotype in human and canine osteosarcoma. no no
16008557 Inhibition of urokinase receptor gene expression and cell invasion by anti-uPAR DNAzymes in osteosarcoma cells. yes no
17980359 Icariside II from Epimedium koreanum inhibits hypoxia-inducible factor-1alpha in human osteosarcoma cells. no no
23201449 Phyllanthus urinaria suppresses human osteosarcoma cell invasion and migration by transcriptionally inhibiting u-PA via ERK and Akt signaling pathways. no no
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