General Information
| Gene ID | 5335 |
|---|---|
| Gene Symbol | PLCG1 |
| Gene Name | phospholipase C, gamma 1 |
| Gene Type | protein-coding |
| Cytoband | 20q12-q13.1 |
| Ensembl ID | ENSG00000124181 |
| #miR regulators | 8 |
| Omim ID | 172420 |
| Gene ontology |
GO:0000186: activation of MAPKK activity GO:0001701: in utero embryonic development GO:0007596: blood coagulation GO:0007165: signal transduction GO:0035556: intracellular signal transduction GO:0007173: epidermal growth factor receptor signaling pathway GO:0007202: activation of phospholipase C activity GO:0007411: axon guidance GO:0008543: fibroblast growth factor receptor signaling pathway GO:0009395: phospholipid catabolic process GO:0010634: positive regulation of epithelial cell migration GO:0019048: modulation by virus of host morphology or physiology GO:0019221: cytokine-mediated signaling pathway GO:0050852: T cell receptor signaling pathway GO:0038095: Fc-epsilon receptor signaling pathway GO:0038096: Fc-gamma receptor signaling pathway involved in phagocytosis GO:0043536: positive regulation of blood vessel endothelial cell migration GO:0043647: inositol phosphate metabolic process GO:0044281: small molecule metabolic process GO:0045087: innate immune response GO:0045766: positive regulation of angiogenesis GO:0048011: neurotrophin TRK receptor signaling pathway GO:0050900: leukocyte migration GO:0071364: cellular response to epidermal growth factor stimulus GO:0005886: plasma membrane GO:0001726: ruffle GO:0005829: cytosol GO:0005737: cytoplasm GO:0008180: COP9 signalosome GO:0030027: lamellipodium GO:0005515: protein binding GO:0005509: calcium ion binding GO:0004435: phosphatidylinositol phospholipase C activity GO:0004629: phospholipase C activity GO:0005057: receptor signaling protein activity GO:0005168: neurotrophin TRKA receptor binding GO:0005543: phospholipid binding GO:0030971: receptor tyrosine kinase binding GO:0035254: glutamate receptor binding |
| KEGG pathways |
562: Inositol phosphate metabolism 1100: Metabolic pathways 4012: ErbB signaling pathway 4020: Calcium signaling pathway 4070: Phosphatidylinositol signaling system 4370: VEGF signaling pathway 4650: Natural killer cell mediated cytotoxicity 4660: T cell receptor signaling pathway 4664: Fc epsilon RI signaling pathway 4666: Fc gamma R-mediated phagocytosis 4670: Leukocyte transendothelial migration 4722: Neurotrophin signaling pathway 5110: Vibrio cholerae infection 5120: Epithelial cell signaling in Helicobacter pylori infection 5200: Pathways in cancer 5214: Glioma 5223: Non-small cell lung cancer |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 8276785 | Interleukin 1 alpha stimulates nuclear phospholipase C in human osteosarcoma SaOS-2 cells. | no | no |
| title | all | all |