Results for PLCG1

General Information

Gene ID 5335
Gene Symbol PLCG1
Gene Name phospholipase C, gamma 1
Gene Type protein-coding
Cytoband 20q12-q13.1
Ensembl ID ENSG00000124181
#miR regulators 8
Omim ID 172420
Gene ontology GO:0000186: activation of MAPKK activity
GO:0001701: in utero embryonic development
GO:0007596: blood coagulation
GO:0007165: signal transduction
GO:0035556: intracellular signal transduction
GO:0007173: epidermal growth factor receptor signaling pathway
GO:0007202: activation of phospholipase C activity
GO:0007411: axon guidance
GO:0008543: fibroblast growth factor receptor signaling pathway
GO:0009395: phospholipid catabolic process
GO:0010634: positive regulation of epithelial cell migration
GO:0019048: modulation by virus of host morphology or physiology
GO:0019221: cytokine-mediated signaling pathway
GO:0050852: T cell receptor signaling pathway
GO:0038095: Fc-epsilon receptor signaling pathway
GO:0038096: Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0043536: positive regulation of blood vessel endothelial cell migration
GO:0043647: inositol phosphate metabolic process
GO:0044281: small molecule metabolic process
GO:0045087: innate immune response
GO:0045766: positive regulation of angiogenesis
GO:0048011: neurotrophin TRK receptor signaling pathway
GO:0050900: leukocyte migration
GO:0071364: cellular response to epidermal growth factor stimulus
GO:0005886: plasma membrane
GO:0001726: ruffle
GO:0005829: cytosol
GO:0005737: cytoplasm
GO:0008180: COP9 signalosome
GO:0030027: lamellipodium
GO:0005515: protein binding
GO:0005509: calcium ion binding
GO:0004435: phosphatidylinositol phospholipase C activity
GO:0004629: phospholipase C activity
GO:0005057: receptor signaling protein activity
GO:0005168: neurotrophin TRKA receptor binding
GO:0005543: phospholipid binding
GO:0030971: receptor tyrosine kinase binding
GO:0035254: glutamate receptor binding
KEGG pathways 562: Inositol phosphate metabolism
1100: Metabolic pathways
4012: ErbB signaling pathway
4020: Calcium signaling pathway
4070: Phosphatidylinositol signaling system
4370: VEGF signaling pathway
4650: Natural killer cell mediated cytotoxicity
4660: T cell receptor signaling pathway
4664: Fc epsilon RI signaling pathway
4666: Fc gamma R-mediated phagocytosis
4670: Leukocyte transendothelial migration
4722: Neurotrophin signaling pathway
5110: Vibrio cholerae infection
5120: Epithelial cell signaling in Helicobacter pylori infection
5200: Pathways in cancer
5214: Glioma
5223: Non-small cell lung cancer

PubMed abstracts associated with PLCG1

PMID Title Tumor Value
8276785 Interleukin 1 alpha stimulates nuclear phospholipase C in human osteosarcoma SaOS-2 cells. no no
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