Results for ATR

General Information

Gene ID 545
Gene Symbol ATR
Gene Name ataxia telangiectasia and Rad3 related
Gene Type protein-coding
Cytoband 3q23
Ensembl ID ENSG00000175054
#miR regulators ---
Omim ID 210600 601215 614564
Gene ontology GO:0006260: DNA replication
GO:0000077: DNA damage checkpoint
GO:0006281: DNA repair
GO:0006974: response to DNA damage stimulus
GO:0007049: cell cycle
GO:0007275: multicellular organismal development
GO:0008156: negative regulation of DNA replication
GO:0018105: peptidyl-serine phosphorylation
GO:0034644: cellular response to UV
GO:0043393: regulation of protein binding
GO:0043517: positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0046777: protein autophosphorylation
GO:0071480: cellular response to gamma radiation
GO:0090399: replicative senescence
GO:0001741: XY body
GO:0005654: nucleoplasm
GO:0005694: chromosome
GO:0016605: PML body
GO:0005515: protein binding
GO:0003677: DNA binding
GO:0004672: protein kinase activity
GO:0004674: protein serine/threonine kinase activity
GO:0005524: ATP binding
GO:0032405: MutLalpha complex binding
GO:0032407: MutSalpha complex binding
KEGG pathways 4110: Cell cycle
4115: p53 signaling pathway

PubMed abstracts associated with ATR

PMID Title Tumor Value
15705874 Cdk inhibition in human cells compromises chk1 function and activates a DNA damage response. no no
title all all