General Information
| Gene ID | 54567 |
|---|---|
| Gene Symbol | DLL4 |
| Gene Name | delta-like 4 (Drosophila) |
| Gene Type | protein-coding |
| Cytoband | 15q14 |
| Ensembl ID | ENSG00000128917 |
| #miR regulators | 13 |
| Omim ID | 605185 |
| Gene ontology |
GO:0000122: negative regulation of transcription from RNA polymerase II promoter GO:0001525: angiogenesis GO:0001569: patterning of blood vessels GO:0001974: blood vessel remodeling GO:0003208: cardiac ventricle morphogenesis GO:0003209: cardiac atrium morphogenesis GO:0003222: ventricular trabecula myocardium morphogenesis GO:0003344: pericardium morphogenesis GO:0007165: signal transduction GO:0007219: Notch signaling pathway GO:0007220: Notch receptor processing GO:0008015: blood circulation GO:0008285: negative regulation of cell proliferation GO:0010596: negative regulation of endothelial cell migration GO:0035912: dorsal aorta morphogenesis GO:0035924: cellular response to vascular endothelial growth factor stimulus GO:0044344: cellular response to fibroblast growth factor stimulus GO:0050767: regulation of neurogenesis GO:0061314: Notch signaling involved in heart development GO:0072554: blood vessel lumenization GO:0090051: negative regulation of cell migration involved in sprouting angiogenesis GO:0005886: plasma membrane GO:0016021: integral to membrane GO:0005509: calcium ion binding GO:0005112: Notch binding |
| KEGG pathways |
4330: Notch signaling pathway |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 19228774 | Notch signaling contributes to the pathogenesis of human osteosarcomas. | no | no |
| title | all | all |