Results for PPARG

General Information

Gene ID 5468
Gene Symbol PPARG
Gene Name peroxisome proliferator-activated receptor gamma
Gene Type protein-coding
Cytoband 3p25
Ensembl ID ENSG00000132170
#miR regulators 6
Omim ID 125853 601487 601665 604367 609338
Gene ontology GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0001890: placenta development
GO:0002674: negative regulation of acute inflammatory response
GO:0007165: signal transduction
GO:0006367: transcription initiation from RNA polymerase II promoter
GO:0006629: lipid metabolic process
GO:0006919: activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007507: heart development
GO:0007584: response to nutrient
GO:0008217: regulation of blood pressure
GO:0042493: response to drug
GO:0009409: response to cold
GO:0010467: gene expression
GO:0010745: negative regulation of macrophage derived foam cell differentiation
GO:0010871: negative regulation of receptor biosynthetic process
GO:0010887: negative regulation of cholesterol storage
GO:0010891: negative regulation of sequestering of triglyceride
GO:0015909: long-chain fatty acid transport
GO:0045893: positive regulation of transcription, DNA-dependent
GO:0045892: negative regulation of transcription, DNA-dependent
GO:0019395: fatty acid oxidation
GO:0030224: monocyte differentiation
GO:0030308: negative regulation of cell growth
GO:0030855: epithelial cell differentiation
GO:0031000: response to caffeine
GO:0031100: organ regeneration
GO:0032526: response to retinoic acid
GO:0032869: cellular response to insulin stimulus
GO:0033189: response to vitamin A
GO:0033993: response to lipid
GO:0035357: peroxisome proliferator activated receptor signaling pathway
GO:0042593: glucose homeostasis
GO:0042953: lipoprotein transport
GO:0043627: response to estrogen stimulus
GO:0045087: innate immune response
GO:0045165: cell fate commitment
GO:0045600: positive regulation of fat cell differentiation
GO:0045713: low-density lipoprotein particle receptor biosynthetic process
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0046321: positive regulation of fatty acid oxidation
GO:0048469: cell maturation
GO:0048662: negative regulation of smooth muscle cell proliferation
GO:0048714: positive regulation of oligodendrocyte differentiation
GO:0050872: white fat cell differentiation
GO:0050873: brown fat cell differentiation
GO:0051091: positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051974: negative regulation of telomerase activity
GO:0055088: lipid homeostasis
GO:0055098: response to low-density lipoprotein particle stimulus
GO:0060336: negative regulation of interferon-gamma-mediated signaling pathway
GO:0060694: regulation of cholesterol transporter activity
GO:0071285: cellular response to lithium ion
GO:0005829: cytosol
GO:0005634: nucleus
GO:0005654: nucleoplasm
GO:0005515: protein binding
GO:0001012: RNA polymerase II regulatory region DNA binding
GO:0003677: DNA binding
GO:0003682: chromatin binding
GO:0003700: sequence-specific DNA binding transcription factor activity
GO:0004879: ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003707: steroid hormone receptor activity
GO:0004955: prostaglandin receptor activity
GO:0008144: drug binding
GO:0008270: zinc ion binding
GO:0044212: transcription regulatory region DNA binding
GO:0019899: enzyme binding
GO:0030374: ligand-dependent nuclear receptor transcription coactivator activity
GO:0033613: activating transcription factor binding
GO:0043565: sequence-specific DNA binding
GO:0046965: retinoid X receptor binding
GO:0050544: arachidonic acid binding
KEGG pathways 3320: PPAR signaling pathway
4380: Osteoclast differentiation
5016: Huntington's disease
5200: Pathways in cancer
5216: Thyroid cancer

PubMed abstracts associated with PPARG

PMID Title Tumor Value
11920584 Troglitazione affects survival of human osteosarcoma cells. no no
19996593 Antitumor efficacy of two novel non-thiazolidinedione compounds as peroxisome proliferator-activated receptor-gamma agonists in human osteosarcoma cells in vitro. no no
20371684 Synergistic antitumor effect of the activated PPARgamma and retinoid receptors on human osteosarcoma. no no
title all all