Results for FBXW7

General Information

Gene ID 55294
Gene Symbol FBXW7
Gene Name F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
Gene Type protein-coding
Cytoband 4q31.3
Ensembl ID ENSG00000109670
#miR regulators 17
Omim ID 606278
Gene ontology GO:0001570: vasculogenesis
GO:0001944: vasculature development
GO:0045741: positive regulation of epidermal growth factor-activated receptor activity
GO:0016567: protein ubiquitination
GO:0006974: response to DNA damage stimulus
GO:0007062: sister chromatid cohesion
GO:0007219: Notch signaling pathway
GO:0010868: negative regulation of triglyceride biosynthetic process
GO:0010883: regulation of lipid storage
GO:0050821: protein stabilization
GO:0019048: modulation by virus of host morphology or physiology
GO:0030324: lung development
GO:0031146: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0032876: negative regulation of DNA endoreduplication
GO:0032880: regulation of protein localization
GO:0034644: cellular response to UV
GO:0045746: negative regulation of Notch signaling pathway
GO:0055088: lipid homeostasis
GO:0070374: positive regulation of ERK1 and ERK2 cascade
GO:2000060: positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:2000346: negative regulation of hepatocyte proliferation
GO:2000639: negative regulation of SREBP signaling pathway
GO:0005783: endoplasmic reticulum
GO:0005654: nucleoplasm
GO:0005730: nucleolus
GO:0005794: Golgi apparatus
GO:0019005: SCF ubiquitin ligase complex
GO:0043234: protein complex
GO:0005515: protein binding
GO:0003700: sequence-specific DNA binding transcription factor activity
KEGG pathways 4120: Ubiquitin mediated proteolysis

PubMed abstracts associated with FBXW7

PMID Title Tumor Value
16938571 hCDC4 variation in osteosarcoma. yes no
title all all