Results for AXL

General Information

Gene ID 558
Gene Symbol AXL
Gene Name AXL receptor tyrosine kinase
Gene Type protein-coding
Cytoband 19q13.1
Ensembl ID ENSG00000167601
#miR regulators 11
Omim ID 109135
Gene ontology GO:0001764: neuron migration
GO:0001779: natural killer cell differentiation
GO:0001961: positive regulation of cytokine-mediated signaling pathway
GO:0001974: blood vessel remodeling
GO:0007165: signal transduction
GO:0006909: phagocytosis
GO:0006954: inflammatory response
GO:0007167: enzyme linked receptor protein signaling pathway
GO:0007283: spermatogenesis
GO:0021885: forebrain cell migration
GO:0030168: platelet activation
GO:0031668: cellular response to extracellular stimulus
GO:0032689: negative regulation of interferon-gamma production
GO:0032720: negative regulation of tumor necrosis factor production
GO:0032825: positive regulation of natural killer cell differentiation
GO:0032940: secretion by cell
GO:0034101: erythrocyte homeostasis
GO:0034446: substrate adhesion-dependent cell spreading
GO:0035457: cellular response to interferon-alpha
GO:0042698: ovulation cycle
GO:0043277: apoptotic cell clearance
GO:0043491: protein kinase B signaling cascade
GO:0043524: negative regulation of neuron apoptotic process
GO:0045087: innate immune response
GO:0048469: cell maturation
GO:0051250: negative regulation of lymphocyte activation
GO:0051897: positive regulation of protein kinase B signaling cascade
GO:0060068: vagina development
GO:0071222: cellular response to lipopolysaccharide
GO:0097028: dendritic cell differentiation
GO:2000669: negative regulation of dendritic cell apoptotic process
GO:0005887: integral to plasma membrane
GO:0005615: extracellular space
GO:0009986: cell surface
GO:0005515: protein binding
GO:0001786: phosphatidylserine binding
GO:0004714: transmembrane receptor protein tyrosine kinase activity
GO:0005524: ATP binding
GO:0046982: protein heterodimerization activity
KEGG pathways ---

PubMed abstracts associated with AXL

PMID Title Tumor Value
14669798 Biological properties and gene expression associated with metastatic potential of human osteosarcoma. no no
23527720 Knockdown of AXL receptor tyrosine kinase in osteosarcoma cells leads to decreased proliferation and increased apoptosis. yes no
23684620 Gas6/Axl mediates tumor cell apoptosis, migration and invasion and predicts the clinical outcome of osteosarcoma patients. yes yes
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