General Information
Gene ID | 558 |
---|---|
Gene Symbol | AXL |
Gene Name | AXL receptor tyrosine kinase |
Gene Type | protein-coding |
Cytoband | 19q13.1 |
Ensembl ID | ENSG00000167601 |
#miR regulators | 11 |
Omim ID | 109135 |
Gene ontology |
GO:0001764: neuron migration GO:0001779: natural killer cell differentiation GO:0001961: positive regulation of cytokine-mediated signaling pathway GO:0001974: blood vessel remodeling GO:0007165: signal transduction GO:0006909: phagocytosis GO:0006954: inflammatory response GO:0007167: enzyme linked receptor protein signaling pathway GO:0007283: spermatogenesis GO:0021885: forebrain cell migration GO:0030168: platelet activation GO:0031668: cellular response to extracellular stimulus GO:0032689: negative regulation of interferon-gamma production GO:0032720: negative regulation of tumor necrosis factor production GO:0032825: positive regulation of natural killer cell differentiation GO:0032940: secretion by cell GO:0034101: erythrocyte homeostasis GO:0034446: substrate adhesion-dependent cell spreading GO:0035457: cellular response to interferon-alpha GO:0042698: ovulation cycle GO:0043277: apoptotic cell clearance GO:0043491: protein kinase B signaling cascade GO:0043524: negative regulation of neuron apoptotic process GO:0045087: innate immune response GO:0048469: cell maturation GO:0051250: negative regulation of lymphocyte activation GO:0051897: positive regulation of protein kinase B signaling cascade GO:0060068: vagina development GO:0071222: cellular response to lipopolysaccharide GO:0097028: dendritic cell differentiation GO:2000669: negative regulation of dendritic cell apoptotic process GO:0005887: integral to plasma membrane GO:0005615: extracellular space GO:0009986: cell surface GO:0005515: protein binding GO:0001786: phosphatidylserine binding GO:0004714: transmembrane receptor protein tyrosine kinase activity GO:0005524: ATP binding GO:0046982: protein heterodimerization activity |
KEGG pathways | --- |
PMID | Title | Tumor | Value |
---|---|---|---|
14669798 | Biological properties and gene expression associated with metastatic potential of human osteosarcoma. | no | no |
23527720 | Knockdown of AXL receptor tyrosine kinase in osteosarcoma cells leads to decreased proliferation and increased apoptosis. | yes | no |
23684620 | Gas6/Axl mediates tumor cell apoptosis, migration and invasion and predicts the clinical outcome of osteosarcoma patients. | yes | yes |
title | all | all |