Results for MAPK7

General Information

Gene ID 5598
Gene Symbol MAPK7
Gene Name mitogen-activated protein kinase 7
Gene Type protein-coding
Cytoband 17p11.2
Ensembl ID ENSG00000166484
#miR regulators 6
Omim ID 602521
Gene ontology GO:0002224: toll-like receptor signaling pathway
GO:0002755: MyD88-dependent toll-like receptor signaling pathway
GO:0002756: MyD88-independent toll-like receptor signaling pathway
GO:0006915: apoptotic process
GO:0007165: signal transduction
GO:0007049: cell cycle
GO:0018105: peptidyl-serine phosphorylation
GO:0019933: cAMP-mediated signaling
GO:0030154: cell differentiation
GO:0030821: negative regulation of cAMP catabolic process
GO:0034115: negative regulation of heterotypic cell-cell adhesion
GO:0034134: toll-like receptor 2 signaling pathway
GO:0034138: toll-like receptor 3 signaling pathway
GO:0034142: toll-like receptor 4 signaling pathway
GO:0034146: toll-like receptor 5 signaling pathway
GO:0034162: toll-like receptor 9 signaling pathway
GO:0034166: toll-like receptor 10 signaling pathway
GO:0035666: TRIF-dependent toll-like receptor signaling pathway
GO:0036003: positive regulation of transcription from RNA polymerase II promoter in response to stress
GO:0038123: toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124: toll-like receptor TLR6:TLR2 signaling pathway
GO:0045087: innate immune response
GO:0045765: regulation of angiogenesis
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0048011: neurotrophin TRK receptor signaling pathway
GO:0050728: negative regulation of inflammatory response
GO:0051247: positive regulation of protein metabolic process
GO:0051344: negative regulation of cyclic-nucleotide phosphodiesterase activity
GO:0051403: stress-activated MAPK cascade
GO:0051534: negative regulation of NFAT protein import into nucleus
GO:0060761: negative regulation of response to cytokine stimulus
GO:0070301: cellular response to hydrogen peroxide
GO:0071363: cellular response to growth factor stimulus
GO:0071499: cellular response to laminar fluid shear stress
GO:0071560: cellular response to transforming growth factor beta stimulus
GO:1902176: negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress
GO:2000352: negative regulation of endothelial cell apoptotic process
GO:2001240: negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
GO:0005829: cytosol
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005654: nucleoplasm
GO:0016605: PML body
GO:0005515: protein binding
GO:0004707: MAP kinase activity
GO:0051019: mitogen-activated protein kinase binding
GO:0005524: ATP binding
KEGG pathways 4010: MAPK signaling pathway
4540: Gap junction
4722: Neurotrophin signaling pathway
4912: GnRH signaling pathway

PubMed abstracts associated with MAPK7

PMID Title Tumor Value
12550767 Amplification of 17p11.2 approximately p12, including PMP22, TOP3A, and MAPK7, in high-grade osteosarcoma. yes no
22154052 MAPK7 and MAP2K4 as prognostic markers in osteosarcoma. yes yes
22213073 ERK5 regulates invasiveness of osteosarcoma by inducing MMP-9. yes no
title all all