General Information
Gene ID | 5598 |
---|---|
Gene Symbol | MAPK7 |
Gene Name | mitogen-activated protein kinase 7 |
Gene Type | protein-coding |
Cytoband | 17p11.2 |
Ensembl ID | ENSG00000166484 |
#miR regulators | 6 |
Omim ID | 602521 |
Gene ontology |
GO:0002224: toll-like receptor signaling pathway GO:0002755: MyD88-dependent toll-like receptor signaling pathway GO:0002756: MyD88-independent toll-like receptor signaling pathway GO:0006915: apoptotic process GO:0007165: signal transduction GO:0007049: cell cycle GO:0018105: peptidyl-serine phosphorylation GO:0019933: cAMP-mediated signaling GO:0030154: cell differentiation GO:0030821: negative regulation of cAMP catabolic process GO:0034115: negative regulation of heterotypic cell-cell adhesion GO:0034134: toll-like receptor 2 signaling pathway GO:0034138: toll-like receptor 3 signaling pathway GO:0034142: toll-like receptor 4 signaling pathway GO:0034146: toll-like receptor 5 signaling pathway GO:0034162: toll-like receptor 9 signaling pathway GO:0034166: toll-like receptor 10 signaling pathway GO:0035666: TRIF-dependent toll-like receptor signaling pathway GO:0036003: positive regulation of transcription from RNA polymerase II promoter in response to stress GO:0038123: toll-like receptor TLR1:TLR2 signaling pathway GO:0038124: toll-like receptor TLR6:TLR2 signaling pathway GO:0045087: innate immune response GO:0045765: regulation of angiogenesis GO:0045944: positive regulation of transcription from RNA polymerase II promoter GO:0048011: neurotrophin TRK receptor signaling pathway GO:0050728: negative regulation of inflammatory response GO:0051247: positive regulation of protein metabolic process GO:0051344: negative regulation of cyclic-nucleotide phosphodiesterase activity GO:0051403: stress-activated MAPK cascade GO:0051534: negative regulation of NFAT protein import into nucleus GO:0060761: negative regulation of response to cytokine stimulus GO:0070301: cellular response to hydrogen peroxide GO:0071363: cellular response to growth factor stimulus GO:0071499: cellular response to laminar fluid shear stress GO:0071560: cellular response to transforming growth factor beta stimulus GO:1902176: negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress GO:2000352: negative regulation of endothelial cell apoptotic process GO:2001240: negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:0005829: cytosol GO:0005634: nucleus GO:0005737: cytoplasm GO:0005654: nucleoplasm GO:0016605: PML body GO:0005515: protein binding GO:0004707: MAP kinase activity GO:0051019: mitogen-activated protein kinase binding GO:0005524: ATP binding |
KEGG pathways |
4010: MAPK signaling pathway 4540: Gap junction 4722: Neurotrophin signaling pathway 4912: GnRH signaling pathway |
PMID | Title | Tumor | Value |
---|---|---|---|
12550767 | Amplification of 17p11.2 approximately p12, including PMP22, TOP3A, and MAPK7, in high-grade osteosarcoma. | yes | no |
22154052 | MAPK7 and MAP2K4 as prognostic markers in osteosarcoma. | yes | yes |
22213073 | ERK5 regulates invasiveness of osteosarcoma by inducing MMP-9. | yes | no |
title | all | all |