General Information
| Gene ID | 5608 |
|---|---|
| Gene Symbol | MAP2K6 |
| Gene Name | mitogen-activated protein kinase kinase 6 |
| Gene Type | protein-coding |
| Cytoband | 17q24.3 |
| Ensembl ID | ENSG00000108984 |
| #miR regulators | 5 |
| Omim ID | 601254 |
| Gene ontology |
GO:0000187: activation of MAPK activity GO:0002224: toll-like receptor signaling pathway GO:0002755: MyD88-dependent toll-like receptor signaling pathway GO:0002756: MyD88-independent toll-like receptor signaling pathway GO:0006915: apoptotic process GO:0007165: signal transduction GO:0006351: transcription, DNA-dependent GO:0006355: regulation of transcription, DNA-dependent GO:0006975: DNA damage induced protein phosphorylation GO:0007050: cell cycle arrest GO:0042493: response to drug GO:0034134: toll-like receptor 2 signaling pathway GO:0034138: toll-like receptor 3 signaling pathway GO:0034142: toll-like receptor 4 signaling pathway GO:0034146: toll-like receptor 5 signaling pathway GO:0034162: toll-like receptor 9 signaling pathway GO:0034166: toll-like receptor 10 signaling pathway GO:0035666: TRIF-dependent toll-like receptor signaling pathway GO:0035872: nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway GO:0038123: toll-like receptor TLR1:TLR2 signaling pathway GO:0038124: toll-like receptor TLR6:TLR2 signaling pathway GO:0042692: muscle cell differentiation GO:0043065: positive regulation of apoptotic process GO:0045087: innate immune response GO:0051149: positive regulation of muscle cell differentiation GO:0051403: stress-activated MAPK cascade GO:0060048: cardiac muscle contraction GO:0070423: nucleotide-binding oligomerization domain containing signaling pathway GO:0005829: cytosol GO:0005654: nucleoplasm GO:0005856: cytoskeleton GO:0005515: protein binding GO:0004674: protein serine/threonine kinase activity GO:0004708: MAP kinase kinase activity GO:0004713: protein tyrosine kinase activity GO:0005524: ATP binding GO:0019901: protein kinase binding |
| KEGG pathways |
4010: MAPK signaling pathway 4380: Osteoclast differentiation 4620: Toll-like receptor signaling pathway 4664: Fc epsilon RI signaling pathway 4912: GnRH signaling pathway 5014: Amyotrophic lateral sclerosis (ALS) 5145: Toxoplasmosis |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 14669798 | Biological properties and gene expression associated with metastatic potential of human osteosarcoma. | no | no |
| title | all | all |