General Information
Gene ID | 5621 |
---|---|
Gene Symbol | PRNP |
Gene Name | prion protein |
Gene Type | protein-coding |
Cytoband | 20p13 |
Ensembl ID | ENSG00000171867 |
#miR regulators | 17 |
Omim ID | 123400 137440 176640 245300 600072 603218 606688 |
Gene ontology |
GO:0008152: metabolic process GO:0001933: negative regulation of protein phosphorylation GO:0006878: cellular copper ion homeostasis GO:0006979: response to oxidative stress GO:0007050: cell cycle arrest GO:0007411: axon guidance GO:0007611: learning or memory GO:0043066: negative regulation of apoptotic process GO:0046686: response to cadmium ion GO:0032689: negative regulation of interferon-gamma production GO:0032700: negative regulation of interleukin-17 production GO:0032703: negative regulation of interleukin-2 production GO:0051260: protein homooligomerization GO:0043433: negative regulation of sequence-specific DNA binding transcription factor activity GO:0046688: response to copper ion GO:0046007: negative regulation of activated T cell proliferation GO:0050860: negative regulation of T cell receptor signaling pathway GO:0070885: negative regulation of calcineurin-NFAT signaling cascade GO:0005886: plasma membrane GO:0019898: extrinsic to membrane GO:0005783: endoplasmic reticulum GO:0005634: nucleus GO:0005737: cytoplasm GO:0005730: nucleolus GO:0043231: intracellular membrane-bounded organelle GO:0005794: Golgi apparatus GO:0031225: anchored to membrane GO:0045121: membrane raft GO:0005515: protein binding GO:0051087: chaperone binding GO:0005507: copper ion binding GO:0008017: microtubule binding GO:0042802: identical protein binding GO:0015631: tubulin binding GO:0043008: ATP-dependent protein binding |
KEGG pathways |
5020: Prion diseases |
PMID | Title | Tumor | Value |
---|---|---|---|
22147650 | Prion proteins (PRNP and PRND) are over-expressed in osteosarcoma. | yes | no |
title | all | all |