Results for PRNP

General Information

Gene ID 5621
Gene Symbol PRNP
Gene Name prion protein
Gene Type protein-coding
Cytoband 20p13
Ensembl ID ENSG00000171867
#miR regulators 17
Omim ID 123400 137440 176640 245300 600072 603218 606688
Gene ontology GO:0008152: metabolic process
GO:0001933: negative regulation of protein phosphorylation
GO:0006878: cellular copper ion homeostasis
GO:0006979: response to oxidative stress
GO:0007050: cell cycle arrest
GO:0007411: axon guidance
GO:0007611: learning or memory
GO:0043066: negative regulation of apoptotic process
GO:0046686: response to cadmium ion
GO:0032689: negative regulation of interferon-gamma production
GO:0032700: negative regulation of interleukin-17 production
GO:0032703: negative regulation of interleukin-2 production
GO:0051260: protein homooligomerization
GO:0043433: negative regulation of sequence-specific DNA binding transcription factor activity
GO:0046688: response to copper ion
GO:0046007: negative regulation of activated T cell proliferation
GO:0050860: negative regulation of T cell receptor signaling pathway
GO:0070885: negative regulation of calcineurin-NFAT signaling cascade
GO:0005886: plasma membrane
GO:0019898: extrinsic to membrane
GO:0005783: endoplasmic reticulum
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005730: nucleolus
GO:0043231: intracellular membrane-bounded organelle
GO:0005794: Golgi apparatus
GO:0031225: anchored to membrane
GO:0045121: membrane raft
GO:0005515: protein binding
GO:0051087: chaperone binding
GO:0005507: copper ion binding
GO:0008017: microtubule binding
GO:0042802: identical protein binding
GO:0015631: tubulin binding
GO:0043008: ATP-dependent protein binding
KEGG pathways 5020: Prion diseases

PubMed abstracts associated with PRNP

PMID Title Tumor Value
22147650 Prion proteins (PRNP and PRND) are over-expressed in osteosarcoma. yes no
title all all