Results for BAD

General Information

Gene ID 572
Gene Symbol BAD
Gene Name BCL2-associated agonist of cell death
Gene Type protein-coding
Cytoband 11q13.1
Ensembl ID ENSG00000002330
#miR regulators 2
Omim ID 603167
Gene ontology GO:0006915: apoptotic process
GO:0006007: glucose catabolic process
GO:0006919: activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007173: epidermal growth factor receptor signaling pathway
GO:0008543: fibroblast growth factor receptor signaling pathway
GO:0042493: response to drug
GO:0009749: response to glucose stimulus
GO:0010508: positive regulation of autophagy
GO:0010918: positive regulation of mitochondrial membrane potential
GO:0046931: pore complex assembly
GO:0019221: cytokine-mediated signaling pathway
GO:0048015: phosphatidylinositol-mediated signaling
GO:0071260: cellular response to mechanical stimulus
GO:0032024: positive regulation of insulin secretion
GO:0032355: response to estradiol stimulus
GO:0032570: response to progesterone stimulus
GO:0033133: positive regulation of glucokinase activity
GO:0033574: response to testosterone stimulus
GO:0034201: response to oleic acid
GO:0035774: positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0038095: Fc-epsilon receptor signaling pathway
GO:0042542: response to hydrogen peroxide
GO:0042593: glucose homeostasis
GO:0043065: positive regulation of apoptotic process
GO:0043200: response to amino acid stimulus
GO:0043280: positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0044342: type B pancreatic cell proliferation
GO:0045087: innate immune response
GO:0045471: response to ethanol
GO:0045579: positive regulation of B cell differentiation
GO:0045582: positive regulation of T cell differentiation
GO:0045862: positive regulation of proteolysis
GO:0046031: ADP metabolic process
GO:0046034: ATP metabolic process
GO:0046902: regulation of mitochondrial membrane permeability
GO:0048011: neurotrophin TRK receptor signaling pathway
GO:0050679: positive regulation of epithelial cell proliferation
GO:0051384: response to glucocorticoid stimulus
GO:0051592: response to calcium ion
GO:0060154: cellular process regulating host cell cycle in response to virus
GO:0071247: cellular response to chromate
GO:0071316: cellular response to nicotine
GO:0071396: cellular response to lipid
GO:0071456: cellular response to hypoxia
GO:0090200: positive regulation of release of cytochrome c from mitochondria
GO:0097190: apoptotic signaling pathway
GO:0097191: extrinsic apoptotic signaling pathway
GO:0097193: intrinsic apoptotic signaling pathway
GO:0097202: activation of cysteine-type endopeptidase activity
GO:1900740: positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:2000078: positive regulation of type B pancreatic cell development
GO:2001244: positive regulation of intrinsic apoptotic signaling pathway
GO:0005739: mitochondrion
GO:0005829: cytosol
GO:0005741: mitochondrial outer membrane
GO:0005515: protein binding
GO:0005543: phospholipid binding
GO:0008289: lipid binding
GO:0008656: cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0019901: protein kinase binding
GO:0030346: protein phosphatase 2B binding
GO:0043422: protein kinase B binding
GO:0046982: protein heterodimerization activity
KEGG pathways 4012: ErbB signaling pathway
4210: Apoptosis
4370: VEGF signaling pathway
4510: Focal adhesion
4722: Neurotrophin signaling pathway
4910: Insulin signaling pathway
5010: Alzheimer's disease
5014: Amyotrophic lateral sclerosis (ALS)
5145: Toxoplasmosis
5160: Hepatitis C
5200: Pathways in cancer
5210: Colorectal cancer
5212: Pancreatic cancer
5213: Endometrial cancer
5215: Prostate cancer
5218: Melanoma
5220: Chronic myeloid leukemia
5221: Acute myeloid leukemia
5223: Non-small cell lung cancer

PubMed abstracts associated with BAD

PMID Title Tumor Value
17471233 Sensitization of osteosarcoma cells to apoptosis by oncostatin M depends on STAT5 and p53. no no
21573491 Wogonin triggers apoptosis in human osteosarcoma U-2 OS cells through the endoplasmic reticulum stress, mitochondrial dysfunction and caspase-3-dependent signaling pathways. no no
22009832 Apoptotic effects of curcumin on human osteosarcoma U2OS cells. no no
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