Results for PTH1R

General Information

Gene ID 5745
Gene Symbol PTH1R
Gene Name parathyroid hormone 1 receptor
Gene Type protein-coding
Cytoband 3p22-p21.1
Ensembl ID ENSG00000160801
#miR regulators 4
Omim ID 125350 156400 168468 215045 600002
Gene ontology GO:0001501: skeletal system development
GO:0002062: chondrocyte differentiation
GO:0002076: osteoblast development
GO:0007186: G-protein coupled receptor signaling pathway
GO:0007187: G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007188: adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007189: adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007200: phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204: elevation of cytosolic calcium ion concentration
GO:0007568: aging
GO:0008284: positive regulation of cell proliferation
GO:0008285: negative regulation of cell proliferation
GO:0030282: bone mineralization
GO:0045453: bone resorption
GO:0048469: cell maturation
GO:0060732: positive regulation of inositol phosphate biosynthetic process
GO:0005886: plasma membrane
GO:0005887: integral to plasma membrane
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0016323: basolateral plasma membrane
GO:0016324: apical plasma membrane
GO:0031526: brush border membrane
GO:0043235: receptor complex
GO:0004991: parathyroid hormone receptor activity
GO:0017046: peptide hormone binding
GO:0043621: protein self-association
KEGG pathways 4080: Neuroactive ligand-receptor interaction

PubMed abstracts associated with PTH1R

PMID Title Tumor Value
16475708 Bone-related growth factors and zoledronic acid regulate the PTHrP/PTH.1 receptor bioregulation systems in MG-63 human osteosarcoma cells. no no
17410535 Over-expression of parathyroid hormone Type 1 receptor confers an aggressive phenotype in osteosarcoma. yes no
20156969 Immunohistochemical identification of the PTHR1 parathyroid hormone receptor in normal and neoplastic human tissues. yes no
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