General Information
Gene ID | 578 |
---|---|
Gene Symbol | BAK1 |
Gene Name | BCL2-antagonist/killer 1 |
Gene Type | protein-coding |
Cytoband | 6p21.3 |
Ensembl ID | ENSG00000030110 |
#miR regulators | 11 |
Omim ID | 600516 |
Gene ontology |
GO:0001782: B cell homeostasis GO:0001783: B cell apoptotic process GO:0001836: release of cytochrome c from mitochondria GO:0001974: blood vessel remodeling GO:0002262: myeloid cell homeostasis GO:0002352: B cell negative selection GO:0051726: regulation of cell cycle GO:0006915: apoptotic process GO:0007420: brain development GO:0007568: aging GO:0008053: mitochondrial fusion GO:0008283: cell proliferation GO:0008285: negative regulation of cell proliferation GO:0008635: activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c GO:0042493: response to drug GO:0009620: response to fungus GO:0010046: response to mycotoxin GO:0010225: response to UV-C GO:0010248: establishment or maintenance of transmembrane electrochemical gradient GO:0010332: response to gamma radiation GO:0010524: positive regulation of calcium ion transport into cytosol GO:0010629: negative regulation of gene expression GO:0014070: response to organic cyclic compound GO:0071260: cellular response to mechanical stimulus GO:0031018: endocrine pancreas development GO:0031100: organ regeneration GO:0032471: reduction of endoplasmic reticulum calcium ion concentration GO:0033137: negative regulation of peptidyl-serine phosphorylation GO:0034644: cellular response to UV GO:0035108: limb morphogenesis GO:0042542: response to hydrogen peroxide GO:0043065: positive regulation of apoptotic process GO:0043496: regulation of protein homodimerization activity GO:0043497: regulation of protein heterodimerization activity GO:0045471: response to ethanol GO:0045862: positive regulation of proteolysis GO:0046902: regulation of mitochondrial membrane permeability GO:0048597: post-embryonic camera-type eye morphogenesis GO:0051881: regulation of mitochondrial membrane potential GO:0060068: vagina development GO:0070059: intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0090200: positive regulation of release of cytochrome c from mitochondria GO:0097190: apoptotic signaling pathway GO:0097193: intrinsic apoptotic signaling pathway GO:0097202: activation of cysteine-type endopeptidase activity GO:1900103: positive regulation of endoplasmic reticulum unfolded protein response GO:1901030: positive regulation of mitochondrial outer membrane permeabilization GO:0005739: mitochondrion GO:0005829: cytosol GO:0005783: endoplasmic reticulum GO:0005741: mitochondrial outer membrane GO:0046930: pore complex GO:0031307: integral to mitochondrial outer membrane GO:0005515: protein binding GO:0051087: chaperone binding GO:0046872: metal ion binding GO:0042802: identical protein binding GO:0031072: heat shock protein binding GO:0042803: protein homodimerization activity GO:0046982: protein heterodimerization activity GO:0051400: BH domain binding |
KEGG pathways |
4141: Protein processing in endoplasmic reticulum |
PMID | Title | Tumor | Value |
---|---|---|---|
22009832 | Apoptotic effects of curcumin on human osteosarcoma U2OS cells. | no | no |
23313376 | Pterostilbene exerts antitumor activity against human osteosarcoma cells by inhibiting the JAK2/STAT3 signaling pathway. | no | no |
title | all | all |