Results for BAK1

General Information

Gene ID 578
Gene Symbol BAK1
Gene Name BCL2-antagonist/killer 1
Gene Type protein-coding
Cytoband 6p21.3
Ensembl ID ENSG00000030110
#miR regulators 11
Omim ID 600516
Gene ontology GO:0001782: B cell homeostasis
GO:0001783: B cell apoptotic process
GO:0001836: release of cytochrome c from mitochondria
GO:0001974: blood vessel remodeling
GO:0002262: myeloid cell homeostasis
GO:0002352: B cell negative selection
GO:0051726: regulation of cell cycle
GO:0006915: apoptotic process
GO:0007420: brain development
GO:0007568: aging
GO:0008053: mitochondrial fusion
GO:0008283: cell proliferation
GO:0008285: negative regulation of cell proliferation
GO:0008635: activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
GO:0042493: response to drug
GO:0009620: response to fungus
GO:0010046: response to mycotoxin
GO:0010225: response to UV-C
GO:0010248: establishment or maintenance of transmembrane electrochemical gradient
GO:0010332: response to gamma radiation
GO:0010524: positive regulation of calcium ion transport into cytosol
GO:0010629: negative regulation of gene expression
GO:0014070: response to organic cyclic compound
GO:0071260: cellular response to mechanical stimulus
GO:0031018: endocrine pancreas development
GO:0031100: organ regeneration
GO:0032471: reduction of endoplasmic reticulum calcium ion concentration
GO:0033137: negative regulation of peptidyl-serine phosphorylation
GO:0034644: cellular response to UV
GO:0035108: limb morphogenesis
GO:0042542: response to hydrogen peroxide
GO:0043065: positive regulation of apoptotic process
GO:0043496: regulation of protein homodimerization activity
GO:0043497: regulation of protein heterodimerization activity
GO:0045471: response to ethanol
GO:0045862: positive regulation of proteolysis
GO:0046902: regulation of mitochondrial membrane permeability
GO:0048597: post-embryonic camera-type eye morphogenesis
GO:0051881: regulation of mitochondrial membrane potential
GO:0060068: vagina development
GO:0070059: intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0090200: positive regulation of release of cytochrome c from mitochondria
GO:0097190: apoptotic signaling pathway
GO:0097193: intrinsic apoptotic signaling pathway
GO:0097202: activation of cysteine-type endopeptidase activity
GO:1900103: positive regulation of endoplasmic reticulum unfolded protein response
GO:1901030: positive regulation of mitochondrial outer membrane permeabilization
GO:0005739: mitochondrion
GO:0005829: cytosol
GO:0005783: endoplasmic reticulum
GO:0005741: mitochondrial outer membrane
GO:0046930: pore complex
GO:0031307: integral to mitochondrial outer membrane
GO:0005515: protein binding
GO:0051087: chaperone binding
GO:0046872: metal ion binding
GO:0042802: identical protein binding
GO:0031072: heat shock protein binding
GO:0042803: protein homodimerization activity
GO:0046982: protein heterodimerization activity
GO:0051400: BH domain binding
KEGG pathways 4141: Protein processing in endoplasmic reticulum

PubMed abstracts associated with BAK1

PMID Title Tumor Value
22009832 Apoptotic effects of curcumin on human osteosarcoma U2OS cells. no no
23313376 Pterostilbene exerts antitumor activity against human osteosarcoma cells by inhibiting the JAK2/STAT3 signaling pathway. no no
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