General Information
Gene ID | 5879 |
---|---|
Gene Symbol | RAC1 |
Gene Name | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) |
Gene Type | protein-coding |
Cytoband | 7p22 |
Ensembl ID | ENSG00000136238 |
#miR regulators | 7 |
Omim ID | 602048 |
Gene ontology |
GO:0002093: auditory receptor cell morphogenesis GO:0002551: mast cell chemotaxis GO:0003382: epithelial cell morphogenesis GO:0030036: actin cytoskeleton organization GO:0007596: blood coagulation GO:0007155: cell adhesion GO:0035556: intracellular signal transduction GO:0006928: cellular component movement GO:0006954: inflammatory response GO:0006972: hyperosmotic response GO:0007160: cell-matrix adhesion GO:0007264: small GTPase mediated signal transduction GO:0009653: anatomical structure morphogenesis GO:0007411: axon guidance GO:0008283: cell proliferation GO:0030041: actin filament polymerization GO:0016032: viral process GO:0009611: response to wounding GO:0010310: regulation of hydrogen peroxide metabolic process GO:0010592: positive regulation of lamellipodium assembly GO:0021799: cerebral cortex radially oriented cell migration GO:0021831: embryonic olfactory bulb interneuron precursor migration GO:0030032: lamellipodium assembly GO:0030168: platelet activation GO:0030334: regulation of cell migration GO:0030838: positive regulation of actin filament polymerization GO:0031295: T cell costimulation GO:0031529: ruffle organization GO:0032707: negative regulation of interleukin-23 production GO:0034446: substrate adhesion-dependent cell spreading GO:0035025: positive regulation of Rho protein signal transduction GO:0038095: Fc-epsilon receptor signaling pathway GO:0038096: Fc-gamma receptor signaling pathway involved in phagocytosis GO:0043065: positive regulation of apoptotic process GO:0043552: positive regulation of phosphatidylinositol 3-kinase activity GO:0043652: engulfment of apoptotic cell GO:0045087: innate immune response GO:0045216: cell-cell junction organization GO:0045453: bone resorption GO:0045740: positive regulation of DNA replication GO:0048011: neurotrophin TRK receptor signaling pathway GO:0048261: negative regulation of receptor-mediated endocytosis GO:0048532: anatomical structure arrangement GO:0048813: dendrite morphogenesis GO:0048870: cell motility GO:0050690: regulation of defense response to virus by virus GO:0051668: localization within membrane GO:0060071: Wnt receptor signaling pathway, planar cell polarity pathway GO:0060263: regulation of respiratory burst GO:0071542: dopaminergic neuron differentiation GO:0090103: cochlea morphogenesis GO:0097178: ruffle assembly GO:0097190: apoptotic signaling pathway GO:0005886: plasma membrane GO:0000139: Golgi membrane GO:0001891: phagocytic cup GO:0005829: cytosol GO:0005802: trans-Golgi network GO:0019897: extrinsic to plasma membrane GO:0030027: lamellipodium GO:0032587: ruffle membrane GO:0042470: melanosome GO:0005515: protein binding GO:0003924: GTPase activity GO:0005525: GTP binding GO:0019899: enzyme binding GO:0017137: Rab GTPase binding GO:0019901: protein kinase binding GO:0030742: GTP-dependent protein binding GO:0031996: thioesterase binding |
KEGG pathways |
4010: MAPK signaling pathway 4062: Chemokine signaling pathway 4145: Phagosome 4310: Wnt signaling pathway 4360: Axon guidance 4370: VEGF signaling pathway 4380: Osteoclast differentiation 4510: Focal adhesion 4520: Adherens junction 4620: Toll-like receptor signaling pathway 4650: Natural killer cell mediated cytotoxicity 4662: B cell receptor signaling pathway 4664: Fc epsilon RI signaling pathway 4666: Fc gamma R-mediated phagocytosis 4670: Leukocyte transendothelial migration 4722: Neurotrophin signaling pathway 4810: Regulation of actin cytoskeleton 4972: Pancreatic secretion 5014: Amyotrophic lateral sclerosis (ALS) 5100: Bacterial invasion of epithelial cells 5120: Epithelial cell signaling in Helicobacter pylori infection 5131: Shigellosis 5200: Pathways in cancer 5210: Colorectal cancer 5211: Renal cell carcinoma 5212: Pancreatic cancer 5416: Viral myocarditis |
PMID | Title | Tumor | Value |
---|---|---|---|
21874265 | Vasodilator-stimulated phosphoprotein regulates osteosarcoma cell migration. | no | no |
22128168 | Dissection of Wnt5a-Ror2 signaling leading to matrix metalloproteinase (MMP-13) expression. | no | no |
title | all | all |