General Information
| Gene ID | 6241 |
|---|---|
| Gene Symbol | RRM2 |
| Gene Name | ribonucleotide reductase M2 |
| Gene Type | protein-coding |
| Cytoband | 2p25-p24 |
| Ensembl ID | ENSG00000171848 |
| #miR regulators | 17 |
| Omim ID | 180390 |
| Gene ontology |
GO:0006260: DNA replication GO:0000082: G1/S transition of mitotic cell cycle GO:0000083: regulation of transcription involved in G1/S phase of mitotic cell cycle GO:0000278: mitotic cell cycle GO:0009186: deoxyribonucleoside diphosphate metabolic process GO:0009263: deoxyribonucleotide biosynthetic process GO:0015949: nucleobase-containing small molecule interconversion GO:0044281: small molecule metabolic process GO:0051290: protein heterotetramerization GO:0055086: nucleobase-containing small molecule metabolic process GO:0005829: cytosol GO:0005737: cytoplasm GO:0005654: nucleoplasm GO:0005515: protein binding GO:0004748: ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor GO:0046914: transition metal ion binding |
| KEGG pathways |
230: Purine metabolism 240: Pyrimidine metabolism 480: Glutathione metabolism 1100: Metabolic pathways 4115: p53 signaling pathway |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 17660802 | Prognostic significance of drug-regulated genes in high-grade osteosarcoma. | yes | yes |
| title | all | all |