Results for RXRA

General Information

Gene ID 6256
Gene Symbol RXRA
Gene Name retinoid X receptor, alpha
Gene Type protein-coding
Cytoband 9q34.3
Ensembl ID ENSG00000186350 ENSG00000269571
#miR regulators 4
Omim ID 180245
Gene ontology GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0001701: in utero embryonic development
GO:0001893: maternal placenta development
GO:0006367: transcription initiation from RNA polymerase II promoter
GO:0006766: vitamin metabolic process
GO:0007566: embryo implantation
GO:0008203: cholesterol metabolic process
GO:0010467: gene expression
GO:0019048: modulation by virus of host morphology or physiology
GO:0032526: response to retinoic acid
GO:0035357: peroxisome proliferator activated receptor signaling pathway
GO:0044255: cellular lipid metabolic process
GO:0044281: small molecule metabolic process
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0048384: retinoic acid receptor signaling pathway
GO:0055010: ventricular cardiac muscle tissue morphogenesis
GO:0055012: ventricular cardiac muscle cell differentiation
GO:0060038: cardiac muscle cell proliferation
GO:0060528: secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
GO:0060687: regulation of branching involved in prostate gland morphogenesis
GO:0000790: nuclear chromatin
GO:0005634: nucleus
GO:0005654: nucleoplasm
GO:0005515: protein binding
GO:0003677: DNA binding
GO:0003700: sequence-specific DNA binding transcription factor activity
GO:0004879: ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003707: steroid hormone receptor activity
GO:0003708: retinoic acid receptor activity
GO:0003713: transcription coactivator activity
GO:0004886: 9-cis retinoic acid receptor activity
GO:0008270: zinc ion binding
GO:0044212: transcription regulatory region DNA binding
GO:0019899: enzyme binding
GO:0031490: chromatin DNA binding
GO:0042809: vitamin D receptor binding
GO:0043565: sequence-specific DNA binding
GO:0044323: retinoic acid-responsive element binding
GO:0046982: protein heterodimerization activity
GO:0070644: vitamin D response element binding
KEGG pathways 3320: PPAR signaling pathway
4920: Adipocytokine signaling pathway
4976: Bile secretion
5160: Hepatitis C
5200: Pathways in cancer
5216: Thyroid cancer
5222: Small cell lung cancer
5223: Non-small cell lung cancer

PubMed abstracts associated with RXRA

PMID Title Tumor Value
7685168 Reverse transcription-polymerase chain reaction assay demonstrates that the 9-cis retinoic acid receptor alpha is expressed in human osteoblasts. no no
20371684 Synergistic antitumor effect of the activated PPARgamma and retinoid receptors on human osteosarcoma. no no
22542077 Clinicopathologic correlation of vitamin D receptor expression with retinoid X receptor and MIB-1 expression in primary and metastatic osteosarcoma. yes yes
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