General Information
Gene ID | 6256 |
---|---|
Gene Symbol | RXRA |
Gene Name | retinoid X receptor, alpha |
Gene Type | protein-coding |
Cytoband | 9q34.3 |
Ensembl ID | ENSG00000186350 ENSG00000269571 |
#miR regulators | 4 |
Omim ID | 180245 |
Gene ontology |
GO:0000122: negative regulation of transcription from RNA polymerase II promoter GO:0001701: in utero embryonic development GO:0001893: maternal placenta development GO:0006367: transcription initiation from RNA polymerase II promoter GO:0006766: vitamin metabolic process GO:0007566: embryo implantation GO:0008203: cholesterol metabolic process GO:0010467: gene expression GO:0019048: modulation by virus of host morphology or physiology GO:0032526: response to retinoic acid GO:0035357: peroxisome proliferator activated receptor signaling pathway GO:0044255: cellular lipid metabolic process GO:0044281: small molecule metabolic process GO:0045944: positive regulation of transcription from RNA polymerase II promoter GO:0048384: retinoic acid receptor signaling pathway GO:0055010: ventricular cardiac muscle tissue morphogenesis GO:0055012: ventricular cardiac muscle cell differentiation GO:0060038: cardiac muscle cell proliferation GO:0060528: secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060687: regulation of branching involved in prostate gland morphogenesis GO:0000790: nuclear chromatin GO:0005634: nucleus GO:0005654: nucleoplasm GO:0005515: protein binding GO:0003677: DNA binding GO:0003700: sequence-specific DNA binding transcription factor activity GO:0004879: ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity GO:0003707: steroid hormone receptor activity GO:0003708: retinoic acid receptor activity GO:0003713: transcription coactivator activity GO:0004886: 9-cis retinoic acid receptor activity GO:0008270: zinc ion binding GO:0044212: transcription regulatory region DNA binding GO:0019899: enzyme binding GO:0031490: chromatin DNA binding GO:0042809: vitamin D receptor binding GO:0043565: sequence-specific DNA binding GO:0044323: retinoic acid-responsive element binding GO:0046982: protein heterodimerization activity GO:0070644: vitamin D response element binding |
KEGG pathways |
3320: PPAR signaling pathway 4920: Adipocytokine signaling pathway 4976: Bile secretion 5160: Hepatitis C 5200: Pathways in cancer 5216: Thyroid cancer 5222: Small cell lung cancer 5223: Non-small cell lung cancer |
PMID | Title | Tumor | Value |
---|---|---|---|
7685168 | Reverse transcription-polymerase chain reaction assay demonstrates that the 9-cis retinoic acid receptor alpha is expressed in human osteoblasts. | no | no |
20371684 | Synergistic antitumor effect of the activated PPARgamma and retinoid receptors on human osteosarcoma. | no | no |
22542077 | Clinicopathologic correlation of vitamin D receptor expression with retinoid X receptor and MIB-1 expression in primary and metastatic osteosarcoma. | yes | yes |
title | all | all |