Results for S100A4

General Information

Gene ID 6275
Gene Symbol S100A4
Gene Name S100 calcium binding protein A4
Gene Type protein-coding
Cytoband 1q21
Ensembl ID ENSG00000196154
#miR regulators ---
Omim ID 114210
Gene ontology GO:0001837: epithelial to mesenchymal transition
GO:0043123: positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0005634: nucleus
GO:0043005: neuron projection
GO:0048471: perinuclear region of cytoplasm
GO:0005515: protein binding
GO:0005509: calcium ion binding
GO:0042802: identical protein binding
GO:0048306: calcium-dependent protein binding
GO:0050786: RAGE receptor binding
KEGG pathways ---

PubMed abstracts associated with S100A4

PMID Title Tumor Value
7607566 Characterization of two splice variants of metastasis-associated human mts1 gene. no no
9858899 Interleukin-1 alpha and basic fibroblast growth factor induction of matrix metalloproteinases and their inhibitors in osteosarcoma cells is modulated by the metastasis associated protein CAPL. no no
10493528 S100A4 involvement in metastasis: deregulation of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in osteosarcoma cells transfected with an anti-S100A4 ribozyme. no no
14713104 S100A4 regulates membrane induced activation of matrix metalloproteinase-2 in osteosarcoma cells. no no
15318945 Sensitization of interferon-gamma induced apoptosis in human osteosarcoma cells by extracellular S100A4. no no
20855150 Small interfering RNA-directed knockdown of S100A4 decreases proliferation and invasiveness of osteosarcoma cells. no no
22292654 Knockdown of S100A4 decreases tumorigenesis and metastasis in osteosarcoma cells by repression of matrix metalloproteinase-9. yes yes
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