Results for CCL5

General Information

Gene ID 6352
Gene Symbol CCL5
Gene Name chemokine (C-C motif) ligand 5
Gene Type protein-coding
Cytoband 17q11.2-q12
Ensembl ID ENSG00000161570 ENSG00000271503
#miR regulators ---
Omim ID 187011
Gene ontology GO:0000165: MAPK cascade
GO:0002407: dendritic cell chemotaxis
GO:0002548: monocyte chemotaxis
GO:0002676: regulation of chronic inflammatory response
GO:0009615: response to virus
GO:0006468: protein phosphorylation
GO:0006816: calcium ion transport
GO:0006874: cellular calcium ion homeostasis
GO:0006887: exocytosis
GO:0006935: chemotaxis
GO:0006954: inflammatory response
GO:0007159: leukocyte cell-cell adhesion
GO:0007267: cell-cell signaling
GO:0009636: response to toxic substance
GO:0010535: positive regulation of activation of JAK2 kinase activity
GO:0010759: positive regulation of macrophage chemotaxis
GO:0010820: positive regulation of T cell chemotaxis
GO:0014068: positive regulation of phosphatidylinositol 3-kinase cascade
GO:0014911: positive regulation of smooth muscle cell migration
GO:0045744: negative regulation of G-protein coupled receptor protein signaling pathway
GO:0030335: positive regulation of cell migration
GO:0031328: positive regulation of cellular biosynthetic process
GO:0031584: activation of phospholipase D activity
GO:0031663: lipopolysaccharide-mediated signaling pathway
GO:0033634: positive regulation of cell-cell adhesion mediated by integrin
GO:0034112: positive regulation of homotypic cell-cell adhesion
GO:0042102: positive regulation of T cell proliferation
GO:0042119: neutrophil activation
GO:0042327: positive regulation of phosphorylation
GO:0042531: positive regulation of tyrosine phosphorylation of STAT protein
GO:0043491: protein kinase B signaling cascade
GO:0043623: cellular protein complex assembly
GO:0043922: negative regulation by host of viral transcription
GO:0044344: cellular response to fibroblast growth factor stimulus
GO:0045070: positive regulation of viral genome replication
GO:0045071: negative regulation of viral genome replication
GO:0045089: positive regulation of innate immune response
GO:0045785: positive regulation of cell adhesion
GO:0045948: positive regulation of translational initiation
GO:0046427: positive regulation of JAK-STAT cascade
GO:0048245: eosinophil chemotaxis
GO:0048246: macrophage chemotaxis
GO:0048661: positive regulation of smooth muscle cell proliferation
GO:0050863: regulation of T cell activation
GO:0050918: positive chemotaxis
GO:0051262: protein tetramerization
GO:0051928: positive regulation of calcium ion transport
GO:0070098: chemokine-mediated signaling pathway
GO:0070100: negative regulation of chemokine-mediated signaling pathway
GO:0070233: negative regulation of T cell apoptotic process
GO:0070234: positive regulation of T cell apoptotic process
GO:0071346: cellular response to interferon-gamma
GO:0071347: cellular response to interleukin-1
GO:0071356: cellular response to tumor necrosis factor
GO:0071407: cellular response to organic cyclic compound
GO:0090026: positive regulation of monocyte chemotaxis
GO:2000110: negative regulation of macrophage apoptotic process
GO:2000503: positive regulation of natural killer cell chemotaxis
GO:0005576: extracellular region
GO:0005615: extracellular space
GO:0005737: cytoplasm
GO:0005515: protein binding
GO:0004435: phosphatidylinositol phospholipase C activity
GO:0004672: protein kinase activity
GO:0008009: chemokine activity
GO:0016004: phospholipase activator activity
GO:0030298: receptor signaling protein tyrosine kinase activator activity
GO:0031726: CCR1 chemokine receptor binding
GO:0031729: CCR4 chemokine receptor binding
GO:0031730: CCR5 chemokine receptor binding
GO:0042056: chemoattractant activity
GO:0042379: chemokine receptor binding
GO:0042803: protein homodimerization activity
GO:0043621: protein self-association
GO:0046817: chemokine receptor antagonist activity
KEGG pathways 4060: Cytokine-cytokine receptor interaction
4062: Chemokine signaling pathway
4620: Toll-like receptor signaling pathway
4621: NOD-like receptor signaling pathway
4623: Cytosolic DNA-sensing pathway
5020: Prion diseases
5120: Epithelial cell signaling in Helicobacter pylori infection
5142: Chagas disease (American trypanosomiasis)
5323: Rheumatoid arthritis

PubMed abstracts associated with CCL5

PMID Title Tumor Value
22506069 CCL5 and CCR5 interaction promotes cell motility in human osteosarcoma. no no
title all all