General Information
Gene ID | 637 |
---|---|
Gene Symbol | BID |
Gene Name | BH3 interacting domain death agonist |
Gene Type | protein-coding |
Cytoband | 22q11.1 |
Ensembl ID | ENSG00000015475 |
#miR regulators | 3 |
Omim ID | 601997 |
Gene ontology |
GO:0001836: release of cytochrome c from mitochondria GO:0006915: apoptotic process GO:0006626: protein targeting to mitochondrion GO:0007420: brain development GO:0008625: extrinsic apoptotic signaling pathway via death domain receptors GO:0008637: apoptotic mitochondrial changes GO:0032355: response to estradiol stimulus GO:0032461: positive regulation of protein oligomerization GO:0032464: positive regulation of protein homooligomerization GO:0034349: glial cell apoptotic process GO:0042127: regulation of cell proliferation GO:0051260: protein homooligomerization GO:0043065: positive regulation of apoptotic process GO:0046902: regulation of mitochondrial membrane permeability GO:0051402: neuron apoptotic process GO:0090150: establishment of protein localization to membrane GO:0090200: positive regulation of release of cytochrome c from mitochondria GO:0097193: intrinsic apoptotic signaling pathway GO:1900740: positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway GO:1901030: positive regulation of mitochondrial outer membrane permeabilization GO:2000045: regulation of G1/S transition of mitotic cell cycle GO:2001238: positive regulation of extrinsic apoptotic signaling pathway GO:2001244: positive regulation of intrinsic apoptotic signaling pathway GO:0016020: membrane GO:0005739: mitochondrion GO:0005829: cytosol GO:0005741: mitochondrial outer membrane GO:0032592: integral to mitochondrial membrane GO:0005515: protein binding GO:0005123: death receptor binding GO:0031625: ubiquitin protein ligase binding |
KEGG pathways |
4115: p53 signaling pathway 4210: Apoptosis 4650: Natural killer cell mediated cytotoxicity 5010: Alzheimer's disease 5014: Amyotrophic lateral sclerosis (ALS) 5200: Pathways in cancer 5416: Viral myocarditis |
PMID | Title | Tumor | Value |
---|---|---|---|
11306692 | The novel triterpenoid CDDO induces apoptosis and differentiation of human osteosarcoma cells by a caspase-8 dependent mechanism. | no | no |
20041491 | Ionizing radiation enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through up-regulations of death receptor 4 (DR4) and death receptor 5 (DR5) in human osteosarcoma cells. | no | no |
23208072 | Heat shock protein 90B1 plays an oncogenic role and is a target of microRNA-223 in human osteosarcoma. | no | no |
title | all | all |