Results for BID

General Information

Gene ID 637
Gene Symbol BID
Gene Name BH3 interacting domain death agonist
Gene Type protein-coding
Cytoband 22q11.1
Ensembl ID ENSG00000015475
#miR regulators 3
Omim ID 601997
Gene ontology GO:0001836: release of cytochrome c from mitochondria
GO:0006915: apoptotic process
GO:0006626: protein targeting to mitochondrion
GO:0007420: brain development
GO:0008625: extrinsic apoptotic signaling pathway via death domain receptors
GO:0008637: apoptotic mitochondrial changes
GO:0032355: response to estradiol stimulus
GO:0032461: positive regulation of protein oligomerization
GO:0032464: positive regulation of protein homooligomerization
GO:0034349: glial cell apoptotic process
GO:0042127: regulation of cell proliferation
GO:0051260: protein homooligomerization
GO:0043065: positive regulation of apoptotic process
GO:0046902: regulation of mitochondrial membrane permeability
GO:0051402: neuron apoptotic process
GO:0090150: establishment of protein localization to membrane
GO:0090200: positive regulation of release of cytochrome c from mitochondria
GO:0097193: intrinsic apoptotic signaling pathway
GO:1900740: positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:1901030: positive regulation of mitochondrial outer membrane permeabilization
GO:2000045: regulation of G1/S transition of mitotic cell cycle
GO:2001238: positive regulation of extrinsic apoptotic signaling pathway
GO:2001244: positive regulation of intrinsic apoptotic signaling pathway
GO:0016020: membrane
GO:0005739: mitochondrion
GO:0005829: cytosol
GO:0005741: mitochondrial outer membrane
GO:0032592: integral to mitochondrial membrane
GO:0005515: protein binding
GO:0005123: death receptor binding
GO:0031625: ubiquitin protein ligase binding
KEGG pathways 4115: p53 signaling pathway
4210: Apoptosis
4650: Natural killer cell mediated cytotoxicity
5010: Alzheimer's disease
5014: Amyotrophic lateral sclerosis (ALS)
5200: Pathways in cancer
5416: Viral myocarditis

PubMed abstracts associated with BID

PMID Title Tumor Value
11306692 The novel triterpenoid CDDO induces apoptosis and differentiation of human osteosarcoma cells by a caspase-8 dependent mechanism. no no
20041491 Ionizing radiation enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through up-regulations of death receptor 4 (DR4) and death receptor 5 (DR5) in human osteosarcoma cells. no no
23208072 Heat shock protein 90B1 plays an oncogenic role and is a target of microRNA-223 in human osteosarcoma. no no
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