Results for SHMT1

General Information

Gene ID 6470
Gene Symbol SHMT1
Gene Name serine hydroxymethyltransferase 1 (soluble)
Gene Type protein-coding
Cytoband 17p11.2
Ensembl ID ENSG00000176974
#miR regulators 4
Omim ID 182144
Gene ontology GO:0006565: L-serine catabolic process
GO:0006766: vitamin metabolic process
GO:0006767: water-soluble vitamin metabolic process
GO:0009113: purine nucleobase biosynthetic process
GO:0019264: glycine biosynthetic process from serine
GO:0034641: cellular nitrogen compound metabolic process
GO:0035999: tetrahydrofolate interconversion
GO:0044281: small molecule metabolic process
GO:0045329: carnitine biosynthetic process
GO:0046655: folic acid metabolic process
GO:0051262: protein tetramerization
GO:0051289: protein homotetramerization
GO:0005739: mitochondrion
GO:0005829: cytosol
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0004372: glycine hydroxymethyltransferase activity
GO:0008732: L-allo-threonine aldolase activity
GO:0016597: amino acid binding
GO:0030170: pyridoxal phosphate binding
GO:0042803: protein homodimerization activity
KEGG pathways 260: Glycine, serine and threonine metabolism
460: Cyanoamino acid metabolism
670: One carbon pool by folate
1100: Metabolic pathways

PubMed abstracts associated with SHMT1

PMID Title Tumor Value
22292074 Identification of novel candidate oncogenes in chromosome region 17p11.2-p12 in human osteosarcoma. yes no
title all all