Results for SMURF2

General Information

Gene ID 64750
Gene Symbol SMURF2
Gene Name SMAD specific E3 ubiquitin protein ligase 2
Gene Type protein-coding
Cytoband 17q22-q23
Ensembl ID ENSG00000108854 ENSG00000262909
#miR regulators 12
Omim ID 605532
Gene ontology GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0042787: protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0006351: transcription, DNA-dependent
GO:0006367: transcription initiation from RNA polymerase II promoter
GO:0006511: ubiquitin-dependent protein catabolic process
GO:0007179: transforming growth factor beta receptor signaling pathway
GO:0010467: gene expression
GO:0045892: negative regulation of transcription, DNA-dependent
GO:0017015: regulation of transforming growth factor beta receptor signaling pathway
GO:0030509: BMP signaling pathway
GO:0030512: negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030579: ubiquitin-dependent SMAD protein catabolic process
GO:0005886: plasma membrane
GO:0000151: ubiquitin ligase complex
GO:0005829: cytosol
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005654: nucleoplasm
GO:0045121: membrane raft
GO:0005515: protein binding
GO:0004842: ubiquitin-protein ligase activity
GO:0005160: transforming growth factor beta receptor binding
GO:0042802: identical protein binding
GO:0046332: SMAD binding
KEGG pathways 4120: Ubiquitin mediated proteolysis
4144: Endocytosis
4350: TGF-beta signaling pathway

PubMed abstracts associated with SMURF2

PMID Title Tumor Value
21945933 RLIM interacts with Smurf2 and promotes TGF-? induced U2OS cell migration. no no
title all all