Results for BMI1

General Information

Gene ID 648
Gene Symbol BMI1
Gene Name BMI1 polycomb ring finger oncogene
Gene Type protein-coding
Cytoband 10p11.23
Ensembl ID ENSG00000168283 ENSG00000269897
#miR regulators 7
Omim ID 164831
Gene ontology GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0006351: transcription, DNA-dependent
GO:0007379: segment specification
GO:0010468: regulation of gene expression
GO:0016568: chromatin modification
GO:0030097: hemopoiesis
GO:0048146: positive regulation of fibroblast proliferation
GO:0051443: positive regulation of ubiquitin-protein ligase activity
GO:0000151: ubiquitin ligase complex
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005730: nucleolus
GO:0031519: PcG protein complex
GO:0035102: PRC1 complex
GO:0005515: protein binding
GO:0008270: zinc ion binding
GO:0071535: RING-like zinc finger domain binding
KEGG pathways ---

PubMed abstracts associated with BMI1

PMID Title Tumor Value
18332870 Cisplatin treatment increases survival and expansion of a highly tumorigenic side-population fraction by upregulating VEGF/Flt1 autocrine signaling. no no
20127006 The knock-down of overexpressed EZH2 and BMI-1 does not prevent osteosarcoma growth. yes no
21311599 Overexpression of BMI-1 promotes cell growth and resistance to cisplatin treatment in osteosarcoma. yes no
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