Results for SKP2

General Information

Gene ID 6502
Gene Symbol SKP2
Gene Name S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
Gene Type protein-coding
Cytoband 5p13
Ensembl ID ENSG00000145604
#miR regulators 1
Omim ID 601436
Gene ontology GO:0000082: G1/S transition of mitotic cell cycle
GO:0000086: G2/M transition of mitotic cell cycle
GO:0000209: protein polyubiquitination
GO:0000278: mitotic cell cycle
GO:0051726: regulation of cell cycle
GO:0008283: cell proliferation
GO:0031145: anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0033148: positive regulation of intracellular estrogen receptor signaling pathway
GO:0048661: positive regulation of smooth muscle cell proliferation
GO:0071460: cellular response to cell-matrix adhesion
GO:0005829: cytosol
GO:0005654: nucleoplasm
GO:0019005: SCF ubiquitin ligase complex
GO:0005515: protein binding
GO:0004842: ubiquitin-protein ligase activity
GO:0042802: identical protein binding
KEGG pathways 4110: Cell cycle
4120: Ubiquitin mediated proteolysis
5200: Pathways in cancer
5222: Small cell lung cancer

PubMed abstracts associated with SKP2

PMID Title Tumor Value
19455146 Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation. no no
20067614 Smoothened as a new therapeutic target for human osteosarcoma. yes no
21506130 Role of GLI2 in the growth of human osteosarcoma. yes yes
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