Results for BMP6

General Information

Gene ID 654
Gene Symbol BMP6
Gene Name bone morphogenetic protein 6
Gene Type protein-coding
Cytoband 6p24-p23
Ensembl ID ENSG00000153162
#miR regulators 14
Omim ID 112266
Gene ontology GO:0001501: skeletal system development
GO:0001649: osteoblast differentiation
GO:0001654: eye development
GO:0001822: kidney development
GO:0001938: positive regulation of endothelial cell proliferation
GO:0001958: endochondral ossification
GO:0003323: type B pancreatic cell development
GO:0006954: inflammatory response
GO:0006955: immune response
GO:0040007: growth
GO:0010862: positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0030501: positive regulation of bone mineralization
GO:0030509: BMP signaling pathway
GO:0030539: male genitalia development
GO:0032349: positive regulation of aldosterone biosynthetic process
GO:0032526: response to retinoic acid
GO:0045603: positive regulation of endothelial cell differentiation
GO:0045666: positive regulation of neuron differentiation
GO:0045669: positive regulation of osteoblast differentiation
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0050679: positive regulation of epithelial cell proliferation
GO:0050714: positive regulation of protein secretion
GO:0051216: cartilage development
GO:0051384: response to glucocorticoid stimulus
GO:0060395: SMAD protein signal transduction
GO:2000105: positive regulation of DNA-dependent DNA replication
GO:0005615: extracellular space
GO:0005737: cytoplasm
GO:0031988: membrane-bounded vesicle
GO:0005125: cytokine activity
GO:0008083: growth factor activity
GO:0046982: protein heterodimerization activity
GO:0070700: BMP receptor binding
KEGG pathways 4340: Hedgehog signaling pathway
4350: TGF-beta signaling pathway

PubMed abstracts associated with BMP6

PMID Title Tumor Value
7641470 The mechanism of bone induction and bone healing by human osteosarcoma cell extracts. no no
9069169 Osteogenic protein-1 stimulates mRNA levels of BMP-6 and decreases mRNA levels of BMP-2 and -4 in human osteosarcoma cells. no no
10627702 Expression of bone morphogenetic proteins and receptors in sarcomas. yes yes
10846544 Expression of bone morphogenetic proteins in human osteogenic and epithelial tumor cells. no no
11986346 The expression of bone morphogenetic proteins in osteosarcoma and its relevance as a prognostic parameter. yes no
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