Results for BMP7

General Information

Gene ID 655
Gene Symbol BMP7
Gene Name bone morphogenetic protein 7
Gene Type protein-coding
Cytoband 20q13
Ensembl ID ENSG00000101144
#miR regulators 3
Omim ID 112267
Gene ontology GO:0001501: skeletal system development
GO:0001503: ossification
GO:0001656: metanephros development
GO:0001657: ureteric bud development
GO:0001707: mesoderm formation
GO:0001823: mesonephros development
GO:0001837: epithelial to mesenchymal transition
GO:0040007: growth
GO:0009880: embryonic pattern specification
GO:0007411: axon guidance
GO:0010664: negative regulation of striated muscle cell apoptotic process
GO:0010800: positive regulation of peptidyl-threonine phosphorylation
GO:0010862: positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0016358: dendrite development
GO:0045893: positive regulation of transcription, DNA-dependent
GO:0045892: negative regulation of transcription, DNA-dependent
GO:0030198: extracellular matrix organization
GO:0030326: embryonic limb morphogenesis
GO:0030501: positive regulation of bone mineralization
GO:0030509: BMP signaling pathway
GO:0030855: epithelial cell differentiation
GO:0032088: negative regulation of NF-kappaB transcription factor activity
GO:0034116: positive regulation of heterotypic cell-cell adhesion
GO:0034504: protein localization to nucleus
GO:0042326: negative regulation of phosphorylation
GO:0042347: negative regulation of NF-kappaB import into nucleus
GO:0042475: odontogenesis of dentin-containing tooth
GO:0043065: positive regulation of apoptotic process
GO:0043401: steroid hormone mediated signaling pathway
GO:0043407: negative regulation of MAP kinase activity
GO:0045665: negative regulation of neuron differentiation
GO:0045666: positive regulation of neuron differentiation
GO:0045669: positive regulation of osteoblast differentiation
GO:0045746: negative regulation of Notch signaling pathway
GO:0045786: negative regulation of cell cycle
GO:0045839: negative regulation of mitosis
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0048596: embryonic camera-type eye morphogenesis
GO:0048754: branching morphogenesis of an epithelial tube
GO:0048762: mesenchymal cell differentiation
GO:0048812: neuron projection morphogenesis
GO:0050768: negative regulation of neurogenesis
GO:0051216: cartilage development
GO:0060272: embryonic skeletal joint morphogenesis
GO:0060393: regulation of pathway-restricted SMAD protein phosphorylation
GO:0060395: SMAD protein signal transduction
GO:0060445: branching involved in salivary gland morphogenesis
GO:0060485: mesenchyme development
GO:0060548: negative regulation of cell death
GO:0060686: negative regulation of prostatic bud formation
GO:0060687: regulation of branching involved in prostate gland morphogenesis
GO:0070487: monocyte aggregation
GO:0071456: cellular response to hypoxia
GO:0072040: negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
GO:0072125: negative regulation of glomerular mesangial cell proliferation
GO:0072133: metanephric mesenchyme morphogenesis
GO:0072134: nephrogenic mesenchyme morphogenesis
GO:0072136: metanephric mesenchymal cell proliferation involved in metanephros development
GO:1900006: positive regulation of dendrite development
GO:1900106: positive regulation of hyaluranon cable assembly
GO:2000121: regulation of removal of superoxide radicals
GO:0005576: extracellular region
GO:0005615: extracellular space
GO:0005515: protein binding
GO:0005125: cytokine activity
GO:0008083: growth factor activity
KEGG pathways 4060: Cytokine-cytokine receptor interaction
4340: Hedgehog signaling pathway
4350: TGF-beta signaling pathway

PubMed abstracts associated with BMP7

PMID Title Tumor Value
7641470 The mechanism of bone induction and bone healing by human osteosarcoma cell extracts. no no
9069169 Osteogenic protein-1 stimulates mRNA levels of BMP-6 and decreases mRNA levels of BMP-2 and -4 in human osteosarcoma cells. no no
10627702 Expression of bone morphogenetic proteins and receptors in sarcomas. yes yes
10846544 Expression of bone morphogenetic proteins in human osteogenic and epithelial tumor cells. no no
11986346 The expression of bone morphogenetic proteins in osteosarcoma and its relevance as a prognostic parameter. yes no
12237108 Malignant reversion of a human osteosarcoma cell line, Saos-2, by inhibition of NFkappaB. no no
15174116 Differential expression of osteogenic factors associated with osteoinductivity of human osteosarcoma cell lines. no no
20225287 Bone deposition, bone resorption, and osteosarcoma. yes yes
20627196 Epidermal growth factor and bone morphogenetic proteins upregulate osteoblast proliferation and osteoblastic markers and inhibit bone nodule formation. no no
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