Results for BMPR2

General Information

Gene ID 659
Gene Symbol BMPR2
Gene Name bone morphogenetic protein receptor, type II (serine/threonine kinase)
Gene Type protein-coding
Cytoband 2q33-q34
Ensembl ID ENSG00000204217
#miR regulators 21
Omim ID 178600 265450 600799
Gene ontology GO:0001707: mesoderm formation
GO:0001938: positive regulation of endothelial cell proliferation
GO:0001946: lymphangiogenesis
GO:0001974: blood vessel remodeling
GO:0003085: negative regulation of systemic arterial blood pressure
GO:0006366: transcription from RNA polymerase II promoter
GO:0007178: transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0009267: cellular response to starvation
GO:0009952: anterior/posterior pattern specification
GO:0010595: positive regulation of endothelial cell migration
GO:0010634: positive regulation of epithelial cell migration
GO:0010862: positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0014916: regulation of lung blood pressure
GO:0030308: negative regulation of cell growth
GO:0030501: positive regulation of bone mineralization
GO:0030509: BMP signaling pathway
GO:0030513: positive regulation of BMP signaling pathway
GO:0042127: regulation of cell proliferation
GO:0045669: positive regulation of osteoblast differentiation
GO:0045906: negative regulation of vasoconstriction
GO:0048010: vascular endothelial growth factor receptor signaling pathway
GO:0048286: lung alveolus development
GO:0060836: lymphatic endothelial cell differentiation
GO:0060840: artery development
GO:0060841: venous blood vessel development
GO:0061298: retina vasculature development in camera-type eye
GO:2000279: negative regulation of DNA biosynthetic process
GO:0005886: plasma membrane
GO:0005887: integral to plasma membrane
GO:0005901: caveola
GO:0009986: cell surface
GO:0005515: protein binding
GO:0005024: transforming growth factor beta-activated receptor activity
GO:0046872: metal ion binding
GO:0005524: ATP binding
GO:0016362: activin receptor activity, type II
KEGG pathways 4060: Cytokine-cytokine receptor interaction
4350: TGF-beta signaling pathway

PubMed abstracts associated with BMPR2

PMID Title Tumor Value
10627702 Expression of bone morphogenetic proteins and receptors in sarcomas. yes yes
title all all