Results for SRF

General Information

Gene ID 6722
Gene Symbol SRF
Gene Name serum response factor (c-fos serum response element-binding transcription factor)
Gene Type protein-coding
Cytoband 6p21.1
Ensembl ID ENSG00000112658
#miR regulators 4
Omim ID 600589
Gene ontology GO:0001569: patterning of blood vessels
GO:0001666: response to hypoxia
GO:0001707: mesoderm formation
GO:0001764: neuron migration
GO:0001829: trophectodermal cell differentiation
GO:0001947: heart looping
GO:0002011: morphogenesis of an epithelial sheet
GO:0002042: cell migration involved in sprouting angiogenesis
GO:0003257: positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0006366: transcription from RNA polymerase II promoter
GO:0007160: cell-matrix adhesion
GO:0007507: heart development
GO:0008306: associative learning
GO:0045987: positive regulation of smooth muscle contraction
GO:0009636: response to toxic substance
GO:0009725: response to hormone stimulus
GO:0010669: epithelial structure maintenance
GO:0010735: positive regulation of transcription via serum response element binding
GO:0021766: hippocampus development
GO:0022028: tangential migration from the subventricular zone to the olfactory bulb
GO:0030038: contractile actin filament bundle assembly
GO:0030155: regulation of cell adhesion
GO:0030168: platelet activation
GO:0030220: platelet formation
GO:0031175: neuron projection development
GO:0033561: regulation of water loss via skin
GO:0034097: response to cytokine stimulus
GO:0035855: megakaryocyte development
GO:0035912: dorsal aorta morphogenesis
GO:0042789: mRNA transcription from RNA polymerase II promoter
GO:0043149: stress fiber assembly
GO:0043589: skin morphogenesis
GO:0045059: positive thymic T cell selection
GO:0045214: sarcomere organization
GO:0045597: positive regulation of cell differentiation
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0046716: muscle cell cellular homeostasis
GO:0048589: developmental growth
GO:0048666: neuron development
GO:0048821: erythrocyte development
GO:0051091: positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051150: regulation of smooth muscle cell differentiation
GO:0051491: positive regulation of filopodium assembly
GO:0055003: cardiac myofibril assembly
GO:0060055: angiogenesis involved in wound healing
GO:0060218: hematopoietic stem cell differentiation
GO:0060261: positive regulation of transcription initiation from RNA polymerase II promoter
GO:0060292: long term synaptic depression
GO:0060347: heart trabecula formation
GO:0060947: cardiac vascular smooth muscle cell differentiation
GO:0061029: eyelid development in camera-type eye
GO:0070830: tight junction assembly
GO:0090009: primitive streak formation
GO:0090136: epithelial cell-cell adhesion
GO:0090398: cellular senescence
GO:1900222: negative regulation of beta-amyloid clearance
GO:0000790: nuclear chromatin
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005515: protein binding
GO:0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000983: RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity
GO:0001076: RNA polymerase II transcription factor binding transcription factor activity
GO:0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001228: RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003700: sequence-specific DNA binding transcription factor activity
GO:0003705: RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0008134: transcription factor binding
GO:0010736: serum response element binding
GO:0031490: chromatin DNA binding
GO:0042803: protein homodimerization activity
KEGG pathways 4010: MAPK signaling pathway

PubMed abstracts associated with SRF

PMID Title Tumor Value
12660819 Immediate-early gene induction by the stresses anisomycin and arsenite in human osteosarcoma cells involves MAPK cascade signaling to Elk-1, CREB and SRF. no no
title all all