General Information
Gene ID | 6722 |
---|---|
Gene Symbol | SRF |
Gene Name | serum response factor (c-fos serum response element-binding transcription factor) |
Gene Type | protein-coding |
Cytoband | 6p21.1 |
Ensembl ID | ENSG00000112658 |
#miR regulators | 4 |
Omim ID | 600589 |
Gene ontology |
GO:0001569: patterning of blood vessels GO:0001666: response to hypoxia GO:0001707: mesoderm formation GO:0001764: neuron migration GO:0001829: trophectodermal cell differentiation GO:0001947: heart looping GO:0002011: morphogenesis of an epithelial sheet GO:0002042: cell migration involved in sprouting angiogenesis GO:0003257: positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation GO:0006366: transcription from RNA polymerase II promoter GO:0007160: cell-matrix adhesion GO:0007507: heart development GO:0008306: associative learning GO:0045987: positive regulation of smooth muscle contraction GO:0009636: response to toxic substance GO:0009725: response to hormone stimulus GO:0010669: epithelial structure maintenance GO:0010735: positive regulation of transcription via serum response element binding GO:0021766: hippocampus development GO:0022028: tangential migration from the subventricular zone to the olfactory bulb GO:0030038: contractile actin filament bundle assembly GO:0030155: regulation of cell adhesion GO:0030168: platelet activation GO:0030220: platelet formation GO:0031175: neuron projection development GO:0033561: regulation of water loss via skin GO:0034097: response to cytokine stimulus GO:0035855: megakaryocyte development GO:0035912: dorsal aorta morphogenesis GO:0042789: mRNA transcription from RNA polymerase II promoter GO:0043149: stress fiber assembly GO:0043589: skin morphogenesis GO:0045059: positive thymic T cell selection GO:0045214: sarcomere organization GO:0045597: positive regulation of cell differentiation GO:0045944: positive regulation of transcription from RNA polymerase II promoter GO:0046716: muscle cell cellular homeostasis GO:0048589: developmental growth GO:0048666: neuron development GO:0048821: erythrocyte development GO:0051091: positive regulation of sequence-specific DNA binding transcription factor activity GO:0051150: regulation of smooth muscle cell differentiation GO:0051491: positive regulation of filopodium assembly GO:0055003: cardiac myofibril assembly GO:0060055: angiogenesis involved in wound healing GO:0060218: hematopoietic stem cell differentiation GO:0060261: positive regulation of transcription initiation from RNA polymerase II promoter GO:0060292: long term synaptic depression GO:0060347: heart trabecula formation GO:0060947: cardiac vascular smooth muscle cell differentiation GO:0061029: eyelid development in camera-type eye GO:0070830: tight junction assembly GO:0090009: primitive streak formation GO:0090136: epithelial cell-cell adhesion GO:0090398: cellular senescence GO:1900222: negative regulation of beta-amyloid clearance GO:0000790: nuclear chromatin GO:0005634: nucleus GO:0005737: cytoplasm GO:0005515: protein binding GO:0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000983: RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity GO:0001076: RNA polymerase II transcription factor binding transcription factor activity GO:0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription GO:0001228: RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription GO:0003700: sequence-specific DNA binding transcription factor activity GO:0003705: RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity GO:0008134: transcription factor binding GO:0010736: serum response element binding GO:0031490: chromatin DNA binding GO:0042803: protein homodimerization activity |
KEGG pathways |
4010: MAPK signaling pathway |
PMID | Title | Tumor | Value |
---|---|---|---|
12660819 | Immediate-early gene induction by the stresses anisomycin and arsenite in human osteosarcoma cells involves MAPK cascade signaling to Elk-1, CREB and SRF. | no | no |
title | all | all |